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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
34.24
Human Site:
T349
Identified Species:
53.81
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
T349
K
K
R
M
M
Y
L
T
T
K
N
A
E
F
D
Chimpanzee
Pan troglodytes
XP_511538
656
72549
T429
K
K
R
M
M
Y
L
T
T
K
N
A
E
F
D
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
T355
K
K
K
M
M
Y
L
T
T
R
N
A
E
F
D
Dog
Lupus familis
XP_548068
552
61535
T325
K
K
R
M
M
Y
L
T
T
K
N
A
E
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
T325
K
K
R
M
M
Y
L
T
T
K
N
A
E
F
D
Rat
Rattus norvegicus
Q62915
909
103240
Q682
M
E
K
T
K
Q
E
Q
Q
A
S
C
T
W
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
T313
K
K
K
M
M
Y
L
T
T
R
N
A
E
F
D
Chicken
Gallus gallus
Q5ZJ00
468
52501
K252
S
P
F
G
K
K
K
K
Y
K
D
K
Y
L
A
Frog
Xenopus laevis
NP_001087762
532
59489
T305
K
K
R
I
M
Y
V
T
T
K
N
A
E
F
D
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
S343
S
M
Y
E
C
K
K
S
E
Q
Y
D
T
A
D
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
K251
S
P
F
G
K
K
K
K
C
K
D
K
Y
L
A
Fruit Fly
Dros. melanogaster
Q24210
898
100893
L681
K
Q
C
R
D
K
Y
L
A
K
H
N
A
I
F
Honey Bee
Apis mellifera
XP_391909
602
67965
S374
K
K
R
K
M
Y
Q
S
K
S
N
G
E
F
D
Nematode Worm
Caenorhab. elegans
P54936
961
108794
M734
N
T
C
N
T
H
C
M
W
F
N
K
K
K
K
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
T329
K
K
R
E
K
Y
E
T
R
K
N
H
Q
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
86.6
100
N.A.
100
0
N.A.
86.6
6.6
86.6
6.6
6.6
13.3
60
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
13.3
100
20
13.3
26.6
66.6
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
7
0
47
7
7
14
% A
% Cys:
0
0
14
0
7
0
7
0
7
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
14
7
0
0
67
% D
% Glu:
0
7
0
14
0
0
14
0
7
0
0
0
54
0
0
% E
% Phe:
0
0
14
0
0
0
0
0
0
7
0
0
0
60
14
% F
% Gly:
0
0
0
14
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
7
7
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
67
60
20
7
27
27
20
14
7
60
0
20
7
7
7
% K
% Leu:
0
0
0
0
0
0
40
7
0
0
0
0
0
14
0
% L
% Met:
7
7
0
40
54
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
7
0
0
0
0
0
0
67
7
0
0
0
% N
% Pro:
0
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
7
7
7
7
0
0
7
0
0
% Q
% Arg:
0
0
47
7
0
0
0
0
7
14
0
0
0
0
0
% R
% Ser:
20
0
0
0
0
0
0
14
0
7
7
0
0
0
0
% S
% Thr:
0
7
0
7
7
0
0
54
47
0
0
0
14
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% W
% Tyr:
0
0
7
0
0
60
7
0
7
0
7
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _