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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP2
All Species:
25.45
Human Site:
S266
Identified Species:
40
UniProt:
Q14168
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14168
NP_005365.3
576
64581
S266
D
Y
D
P
A
R
D
S
L
I
P
C
K
E
A
Chimpanzee
Pan troglodytes
XP_511538
656
72549
S346
D
Y
D
P
A
R
D
S
L
I
P
C
K
E
A
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
N274
D
Y
N
P
Y
N
D
N
L
I
P
C
K
E
A
Dog
Lupus familis
XP_548068
552
61535
S242
D
Y
D
P
A
R
D
S
L
I
P
C
K
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV34
552
61537
S242
D
Y
D
P
A
R
D
S
L
S
P
C
K
E
A
Rat
Rattus norvegicus
Q62915
909
103240
D617
E
Y
D
P
A
K
D
D
L
I
P
C
K
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
N232
D
Y
N
P
Y
N
D
N
L
I
P
C
K
E
A
Chicken
Gallus gallus
Q5ZJ00
468
52501
I194
K
F
Q
T
G
D
V
I
Q
I
I
N
K
D
D
Frog
Xenopus laevis
NP_001087762
532
59489
S222
S
Y
D
P
S
S
D
S
L
I
P
C
K
E
A
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
K245
D
Y
N
P
A
E
D
K
A
I
P
C
K
E
A
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
I193
L
K
F
Q
T
G
D
I
I
Q
I
I
N
K
Q
Fruit Fly
Dros. melanogaster
Q24210
898
100893
E599
D
Y
N
P
L
D
D
E
L
I
P
C
A
Q
A
Honey Bee
Apis mellifera
XP_391909
602
67965
T289
D
Y
D
P
S
E
D
T
L
L
P
C
R
E
I
Nematode Worm
Caenorhab. elegans
P54936
961
108794
D650
D
Y
E
P
S
Q
D
D
L
I
P
C
P
Q
A
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
T246
D
Y
D
P
S
Q
D
T
L
L
P
C
Q
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
66.3
93.4
N.A.
93.4
30.2
N.A.
66.1
36.2
72
36.8
33.5
31.9
42.3
26.9
46
Protein Similarity:
100
82.9
81.7
94.7
N.A.
94.9
43.5
N.A.
80.5
53.1
82.1
55
51.3
43.7
61.9
41.7
65.8
P-Site Identity:
100
100
73.3
100
N.A.
93.3
80
N.A.
73.3
13.3
80
73.3
6.6
60
60
60
60
P-Site Similarity:
100
100
86.6
100
N.A.
93.3
93.3
N.A.
86.6
26.6
86.6
80
20
73.3
86.6
86.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
40
0
0
0
7
0
0
0
7
0
74
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
87
0
0
0
% C
% Asp:
74
0
54
0
0
14
94
14
0
0
0
0
0
7
7
% D
% Glu:
7
0
7
0
0
14
0
7
0
0
0
0
0
74
0
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
14
7
74
14
7
0
0
7
% I
% Lys:
7
7
0
0
0
7
0
7
0
0
0
0
67
7
0
% K
% Leu:
7
0
0
0
7
0
0
0
80
14
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
27
0
0
14
0
14
0
0
0
7
7
0
0
% N
% Pro:
0
0
0
87
0
0
0
0
0
0
87
0
7
0
0
% P
% Gln:
0
0
7
7
0
14
0
0
7
7
0
0
7
14
7
% Q
% Arg:
0
0
0
0
0
27
0
0
0
0
0
0
7
0
0
% R
% Ser:
7
0
0
0
27
7
0
34
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
7
7
0
0
14
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
87
0
0
14
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _