KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
20.61
Human Site:
T210
Identified Species:
32.38
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
T210
R
N
L
T
V
S
N
T
R
T
V
L
L
T
P
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
T210
R
N
L
T
V
S
N
T
R
T
V
V
L
T
P
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
T210
R
N
L
T
V
S
N
T
R
T
V
L
L
T
P
Dog
Lupus familis
XP_850081
1066
122542
T210
R
N
L
T
V
S
N
T
R
T
V
L
L
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
S282
G
G
A
S
N
W
D
S
Y
S
D
H
F
T
I
Rat
Rattus norvegicus
Q6P7A2
1066
122361
T210
R
N
L
T
V
S
N
T
R
T
V
L
L
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
A211
R
N
L
T
V
S
N
A
H
T
V
L
L
T
P
Frog
Xenopus laevis
NP_001084506
1072
122544
A209
K
A
L
T
V
S
N
A
R
T
V
L
L
T
P
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
A213
K
N
L
T
V
S
N
A
R
T
V
L
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
F212
I
T
M
K
K
N
T
F
W
I
L
G
Y
F
V
Honey Bee
Apis mellifera
XP_393070
965
109934
I191
F
L
S
F
I
N
G
I
V
L
E
L
Q
T
E
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
A198
T
D
E
C
D
E
D
A
I
T
E
T
F
N
P
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
S204
L
F
D
I
L
L
Q
S
Y
T
K
E
E
G
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
G237
Y
L
V
S
L
P
V
G
A
K
S
L
V
S
H
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
K188
F
E
L
F
V
T
F
K
P
I
A
E
I
F
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
93.3
100
100
N.A.
6.6
100
N.A.
N.A.
86.6
80
86.6
N.A.
0
13.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
N.A.
86.6
86.6
93.3
N.A.
20
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
27
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
7
0
14
0
0
0
7
0
0
0
0
% D
% Glu:
0
7
7
0
0
7
0
0
0
0
14
14
7
0
7
% E
% Phe:
14
7
0
14
0
0
7
7
0
0
0
0
14
14
0
% F
% Gly:
7
7
0
0
0
0
7
7
0
0
0
7
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
7
% H
% Ile:
7
0
0
7
7
0
0
7
7
14
0
0
7
0
7
% I
% Lys:
14
0
0
7
7
0
0
7
0
7
7
0
0
0
0
% K
% Leu:
7
14
60
0
14
7
0
0
0
7
7
60
54
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
47
0
0
7
14
54
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
60
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% Q
% Arg:
40
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% R
% Ser:
0
0
7
14
0
54
0
14
0
7
7
0
0
7
0
% S
% Thr:
7
7
0
54
0
7
7
34
0
67
0
7
0
67
7
% T
% Val:
0
0
7
0
60
0
7
0
7
0
54
7
7
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
0
0
0
0
14
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _