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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BOP1 All Species: 13.33
Human Site: S642 Identified Species: 29.33
UniProt: Q14137 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14137 NP_056016.1 746 83630 S642 V I C G S Y D S K L V W F D L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P97452 732 82527 S628 I I C G S Y D S K L V W F D L
Rat Rattus norvegicus Q562C2 731 82621 S627 I I C G S Y D S K L V W F D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q7ZXX9 728 83447 S624 L I C G S Y D S K L A W F D M
Zebra Danio Brachydanio rerio A0JMQ0 777 88347 C673 V I C G S Y D C R L A W F D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K0Y1 784 90425 K680 L L V S T Y D K K M L W F D L
Honey Bee Apis mellifera XP_623929 725 84096 R621 I L V G T Y D R K M L W F D L
Nematode Worm Caenorhab. elegans Q9U2A9 674 77363 G578 C W M D L Q M G N K P W K K L
Sea Urchin Strong. purpuratus XP_780573 808 93279 C704 V L I G S Y D C R V S W F D M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04660 807 91686 K702 L I A S S F D K R V L W H D L
Red Bread Mold Neurospora crassa Q7SEM3 779 87695 K674 L I V G S Y D K R L L W H D L
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 83.3 83.5 N.A. N.A. N.A. 67.8 63.7 N.A. 48.5 46.5 43.5 51.4
Protein Similarity: 100 N.A. N.A. N.A. N.A. 89.8 89.5 N.A. N.A. N.A. 80 76.5 N.A. 67 68.9 59.1 68.5
P-Site Identity: 100 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. N.A. N.A. 80 80 N.A. 46.6 53.3 13.3 53.3
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 100 N.A. N.A. N.A. 93.3 86.6 N.A. 80 86.6 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 38.2 38.3
Protein Similarity: N.A. N.A. N.A. N.A. 56.8 56.7
P-Site Identity: N.A. N.A. N.A. N.A. 40 60
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 19 0 0 0 0 % A
% Cys: 10 0 46 0 0 0 0 19 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 91 0 0 0 0 0 0 91 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 73 0 0 % F
% Gly: 0 0 0 73 0 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % H
% Ile: 28 64 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 28 55 10 0 0 10 10 0 % K
% Leu: 37 28 0 0 10 0 0 0 0 55 37 0 0 0 82 % L
% Met: 0 0 10 0 0 0 10 0 0 19 0 0 0 0 19 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 10 37 0 0 0 0 0 0 % R
% Ser: 0 0 0 19 73 0 0 37 0 0 10 0 0 0 0 % S
% Thr: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % T
% Val: 28 0 28 0 0 0 0 0 0 19 28 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 100 0 0 0 % W
% Tyr: 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _