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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK13 All Species: 11.21
Human Site: S411 Identified Species: 27.41
UniProt: Q14004 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14004 NP_003709.3 1512 164923 S411 R R S G K S R S R S P Y S S R
Chimpanzee Pan troglodytes XP_001139939 1512 164915 S411 R R S G K S R S R S P Y S S R
Rhesus Macaque Macaca mulatta XP_001088594 1490 164086 K403 G A E L S R K K K E R A A A A
Dog Lupus familis XP_533082 1377 150158 G364 N T S T P T K G S T E T G A G
Cat Felis silvestris
Mouse Mus musculus Q69ZA1 1511 164590 S412 R R S A K S R S R S P Y S S R
Rat Rattus norvegicus Q3MJK5 1484 163772 V386 R H S S I S P V R L P L N S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425866 1032 115177 E48 H K S R H S K E S P L A A Q E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687417 1286 141523 S302 P Y W R R S P S Y G R H S P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46551 730 82410
Sea Urchin Strong. purpuratus XP_789337 1264 139419 S277 P A T K F H S S I G G E V Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 41.4 82.5 N.A. 95.1 41.6 N.A. N.A. 29.7 N.A. 44 N.A. N.A. N.A. 24.6 32.6
Protein Similarity: 100 99.8 53.5 84.5 N.A. 96.8 53.9 N.A. N.A. 37.9 N.A. 55 N.A. N.A. N.A. 33.3 46.9
P-Site Identity: 100 100 0 6.6 N.A. 93.3 40 N.A. N.A. 13.3 N.A. 20 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 100 26.6 33.3 N.A. 93.3 46.6 N.A. N.A. 33.3 N.A. 33.3 N.A. N.A. N.A. 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 10 0 0 0 0 0 0 0 20 20 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 0 10 0 10 10 10 0 0 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 20 0 0 0 10 0 20 10 0 10 0 10 % G
% His: 10 10 0 0 10 10 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 10 0 10 30 0 30 10 10 0 0 0 0 0 10 % K
% Leu: 0 0 0 10 0 0 0 0 0 10 10 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 20 0 0 0 10 0 20 0 0 10 40 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % Q
% Arg: 40 30 0 20 10 10 30 0 40 0 20 0 0 0 30 % R
% Ser: 0 0 60 10 10 60 10 50 20 30 0 0 40 40 10 % S
% Thr: 0 10 10 10 0 10 0 0 0 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 10 0 0 30 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _