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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK13 All Species: 15.45
Human Site: S1449 Identified Species: 37.78
UniProt: Q14004 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14004 NP_003709.3 1512 164923 S1449 D P S T G P E S T H P L P A K
Chimpanzee Pan troglodytes XP_001139939 1512 164915 S1449 D P S T G P E S T H P L P A K
Rhesus Macaque Macaca mulatta XP_001088594 1490 164086 S1427 F L K A E G S S N S V V H A E
Dog Lupus familis XP_533082 1377 150158 S1314 D P A A G P E S T H P L P A K
Cat Felis silvestris
Mouse Mus musculus Q69ZA1 1511 164590 S1448 D P S T G P E S T H P L P A K
Rat Rattus norvegicus Q3MJK5 1484 163772 G1421 Q P F L K S E G N S N S V V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425866 1032 115177 N970 V I K L P Y F N T M K P K K Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687417 1286 141523 P1224 R M M G A G L P P H A P L G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46551 730 82410 T668 P T Q P S T T T T K S N G S S
Sea Urchin Strong. purpuratus XP_789337 1264 139419 G1202 S K A I F P S G Q Y C K E D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 41.4 82.5 N.A. 95.1 41.6 N.A. N.A. 29.7 N.A. 44 N.A. N.A. N.A. 24.6 32.6
Protein Similarity: 100 99.8 53.5 84.5 N.A. 96.8 53.9 N.A. N.A. 37.9 N.A. 55 N.A. N.A. N.A. 33.3 46.9
P-Site Identity: 100 100 13.3 86.6 N.A. 100 13.3 N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 26.6 93.3 N.A. 100 13.3 N.A. N.A. 20 N.A. 6.6 N.A. N.A. N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 20 10 0 0 0 0 0 10 0 0 50 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 40 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 0 50 0 0 0 0 0 10 0 10 % E
% Phe: 10 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 40 20 0 20 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 50 0 0 10 0 10 % H
% Ile: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 20 0 10 0 0 0 0 10 10 10 10 10 40 % K
% Leu: 0 10 0 20 0 0 10 0 0 0 0 40 10 0 0 % L
% Met: 0 10 10 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 20 0 10 10 0 0 0 % N
% Pro: 10 50 0 10 10 50 0 10 10 0 40 20 40 0 20 % P
% Gln: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 30 0 10 10 20 50 0 20 10 10 0 10 10 % S
% Thr: 0 10 0 30 0 10 10 10 60 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 10 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _