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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK13 All Species: 10.61
Human Site: S1162 Identified Species: 25.93
UniProt: Q14004 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14004 NP_003709.3 1512 164923 S1162 P L G G I Q P S S Q T I Q P K
Chimpanzee Pan troglodytes XP_001139939 1512 164915 S1162 P L G G I Q P S S Q T I Q P K
Rhesus Macaque Macaca mulatta XP_001088594 1490 164086 Q1166 A L T E A S S Q Q Q D S E T M
Dog Lupus familis XP_533082 1377 150158 S1028 P L G G I Q P S S Q S V Q P K
Cat Felis silvestris
Mouse Mus musculus Q69ZA1 1511 164590 P1161 K S L G G V Q P S Q T I Q P K
Rat Rattus norvegicus Q3MJK5 1484 163772 Q1162 A L T E A S S Q Q Q D S E S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_425866 1032 115177 E711 I C C P R Y G E R R Q T E S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687417 1286 141523 P965 G S A N A A D P K S A N S Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46551 730 82410 E409 H D L I G L L E S K E L V D F
Sea Urchin Strong. purpuratus XP_789337 1264 139419 T943 N V Q V D A S T I K L L E N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 41.4 82.5 N.A. 95.1 41.6 N.A. N.A. 29.7 N.A. 44 N.A. N.A. N.A. 24.6 32.6
Protein Similarity: 100 99.8 53.5 84.5 N.A. 96.8 53.9 N.A. N.A. 37.9 N.A. 55 N.A. N.A. N.A. 33.3 46.9
P-Site Identity: 100 100 13.3 86.6 N.A. 53.3 13.3 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 20 100 N.A. 53.3 20 N.A. N.A. 13.3 N.A. 0 N.A. N.A. N.A. 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 10 0 30 20 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 10 0 0 0 20 0 0 10 10 % D
% Glu: 0 0 0 20 0 0 0 20 0 0 10 0 40 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 30 40 20 0 10 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 30 0 0 0 10 0 0 30 0 0 10 % I
% Lys: 10 0 0 0 0 0 0 0 10 20 0 0 0 0 40 % K
% Leu: 0 50 20 0 0 10 10 0 0 0 10 20 0 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 30 0 0 10 0 0 30 20 0 0 0 0 0 40 0 % P
% Gln: 0 0 10 0 0 30 10 20 20 60 10 0 40 10 0 % Q
% Arg: 0 0 0 0 10 0 0 0 10 10 0 0 0 0 0 % R
% Ser: 0 20 0 0 0 20 30 30 50 10 10 20 10 20 0 % S
% Thr: 0 0 20 0 0 0 0 10 0 0 30 10 0 10 0 % T
% Val: 0 10 0 10 0 10 0 0 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _