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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BYSL
All Species:
42.12
Human Site:
Y195
Identified Species:
66.19
UniProt:
Q13895
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13895
NP_004044.3
437
49601
Y195
V
R
E
V
L
S
K
Y
R
S
G
K
L
P
K
Chimpanzee
Pan troglodytes
XP_518469
323
36415
Q95
R
L
G
P
R
M
P
Q
D
G
S
D
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001085599
438
49814
Y195
V
R
E
V
L
S
K
Y
R
S
G
K
L
P
K
Dog
Lupus familis
XP_532135
573
64755
Y331
V
R
E
V
L
S
K
Y
R
S
G
K
L
P
K
Cat
Felis silvestris
Mouse
Mus musculus
O54825
436
49765
Y194
V
R
E
V
L
C
K
Y
R
S
G
K
L
P
K
Rat
Rattus norvegicus
Q80WL2
436
49993
Y194
V
R
E
V
L
C
K
Y
R
S
G
I
L
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418047
388
44132
Q149
M
E
K
I
T
E
K
Q
T
E
V
Q
T
A
L
Frog
Xenopus laevis
NP_001085058
431
49284
Y192
V
K
E
V
L
S
S
Y
R
S
G
K
L
P
K
Zebra Danio
Brachydanio rerio
NP_957400
422
48101
Y178
V
S
K
V
L
S
K
Y
R
S
G
K
L
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51406
436
49948
Y176
V
R
D
V
L
K
R
Y
R
S
G
K
I
P
K
Honey Bee
Apis mellifera
XP_397030
433
50344
Y187
V
R
D
V
L
S
K
Y
R
S
G
K
L
P
K
Nematode Worm
Caenorhab. elegans
Q20932
449
51602
Y197
I
G
Q
Y
M
S
K
Y
R
S
G
K
V
P
K
Sea Urchin
Strong. purpuratus
XP_001175650
430
49345
R189
G
Q
I
L
S
R
Y
R
S
G
K
L
P
K
A
Poplar Tree
Populus trichocarpa
XP_002330743
443
51017
Y176
V
G
E
Y
L
S
K
Y
T
A
G
K
I
P
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38333
483
55118
W224
V
G
S
I
L
K
T
W
T
H
G
K
L
P
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.9
97.4
71.7
N.A.
90.6
90.6
N.A.
N.A.
66.8
73.2
73.2
N.A.
51.7
59.2
49.4
57.2
Protein Similarity:
100
73.9
98.4
74
N.A.
93.5
93.5
N.A.
N.A.
74.8
85.8
84.2
N.A.
68.6
75.7
67.7
74.3
P-Site Identity:
100
0
100
100
N.A.
93.3
86.6
N.A.
N.A.
6.6
86.6
86.6
N.A.
73.3
93.3
60
0
P-Site Similarity:
100
0
100
100
N.A.
93.3
86.6
N.A.
N.A.
33.3
93.3
93.3
N.A.
93.3
100
86.6
13.3
Percent
Protein Identity:
44.4
N.A.
N.A.
N.A.
35.4
N.A.
Protein Similarity:
65.9
N.A.
N.A.
N.A.
56.5
N.A.
P-Site Identity:
66.6
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
80
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
0
0
0
0
0
7
0
0
7
7
0
7
% D
% Glu:
0
7
47
0
0
7
0
0
0
7
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
20
7
0
0
0
0
0
0
14
80
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
7
14
0
0
0
0
0
0
0
7
14
0
0
% I
% Lys:
0
7
14
0
0
14
67
0
0
0
7
74
0
7
80
% K
% Leu:
0
7
0
7
74
0
0
0
0
0
0
7
60
0
7
% L
% Met:
7
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
7
0
0
0
0
0
7
80
0
% P
% Gln:
0
7
7
0
0
0
0
14
0
0
0
7
0
0
0
% Q
% Arg:
7
47
0
0
7
7
7
7
67
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
7
54
7
0
7
67
7
0
0
0
0
% S
% Thr:
0
0
0
0
7
0
7
0
20
0
0
0
7
0
0
% T
% Val:
74
0
0
60
0
0
0
0
0
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
14
0
0
7
74
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _