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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BYSL All Species: 31.52
Human Site: T164 Identified Species: 49.52
UniProt: Q13895 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13895 NP_004044.3 437 49601 T164 E K Q T E V E T V M S E V S G
Chimpanzee Pan troglodytes XP_518469 323 36415 Q64 R I L Q Q A R Q Q Q E E L E A
Rhesus Macaque Macaca mulatta XP_001085599 438 49814 T164 E K Q T E V E T V M S E V S G
Dog Lupus familis XP_532135 573 64755 M300 E K Q T E V E M V M S E V S G
Cat Felis silvestris
Mouse Mus musculus O54825 436 49765 T163 E K Q T E V E T V M S E V S G
Rat Rattus norvegicus Q80WL2 436 49993 T163 E K Q T E V E T V M S E V S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418047 388 44132 E118 G D V E V D P E D E K A L E V
Frog Xenopus laevis NP_001085058 431 49284 T161 E K Q T E V E T M M S E V S G
Zebra Danio Brachydanio rerio NP_957400 422 48101 T147 E K Q T E V G T V L S E V S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P51406 436 49948 T145 E K E A D I H T K I S D E G S
Honey Bee Apis mellifera XP_397030 433 50344 T156 E K K T E I E T Q F S D V G S
Nematode Worm Caenorhab. elegans Q20932 449 51602 L166 Q N D A E L A L S Q V D P N E
Sea Urchin Strong. purpuratus XP_001175650 430 49345 S158 E K K T E V A S Q M T E S G M
Poplar Tree Populus trichocarpa XP_002330743 443 51017 D145 I E K L K K T D A N V S S E L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38333 483 55118 N193 E Q N T S R G N I S S G L K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.9 97.4 71.7 N.A. 90.6 90.6 N.A. N.A. 66.8 73.2 73.2 N.A. 51.7 59.2 49.4 57.2
Protein Similarity: 100 73.9 98.4 74 N.A. 93.5 93.5 N.A. N.A. 74.8 85.8 84.2 N.A. 68.6 75.7 67.7 74.3
P-Site Identity: 100 6.6 100 93.3 N.A. 100 100 N.A. N.A. 0 93.3 86.6 N.A. 26.6 53.3 6.6 46.6
P-Site Similarity: 100 20 100 93.3 N.A. 100 100 N.A. N.A. 6.6 100 93.3 N.A. 60 73.3 33.3 66.6
Percent
Protein Identity: 44.4 N.A. N.A. N.A. 35.4 N.A.
Protein Similarity: 65.9 N.A. N.A. N.A. 56.5 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 7 14 0 7 0 0 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 7 7 0 7 7 0 0 20 0 0 0 % D
% Glu: 74 7 7 7 67 0 47 7 0 7 7 60 7 20 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % F
% Gly: 7 0 0 0 0 0 14 0 0 0 0 7 0 20 47 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 0 14 0 0 7 7 0 0 0 0 0 % I
% Lys: 0 67 20 0 7 7 0 0 7 0 7 0 0 7 0 % K
% Leu: 0 0 7 7 0 7 0 7 0 7 0 0 20 0 7 % L
% Met: 0 0 0 0 0 0 0 7 7 47 0 0 0 0 7 % M
% Asn: 0 7 7 0 0 0 0 7 0 7 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % P
% Gln: 7 7 47 7 7 0 0 7 20 14 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 0 7 7 7 67 7 14 47 20 % S
% Thr: 0 0 0 67 0 0 7 54 0 0 7 0 0 0 0 % T
% Val: 0 0 7 0 7 54 0 0 40 0 14 0 54 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _