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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBB2A All Species: 49.7
Human Site: T290 Identified Species: 99.39
UniProt: Q13885 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13885 NP_001060.1 445 49907 T290 A L T V P E L T Q Q M F D S K
Chimpanzee Pan troglodytes Q8WP14 444 49773 T290 A L T V A E L T Q Q M F D A K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535868 543 59433 T388 A L T V P E L T Q Q M F D S K
Cat Felis silvestris
Mouse Mus musculus Q9ERD7 450 50400 T290 A L T V P E L T Q Q M F D A K
Rat Rattus norvegicus Q6P9T8 445 49782 T290 A L T V P E L T Q Q M F D A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09203 445 49890 T290 A L T V P E L T Q Q M F D S K
Frog Xenopus laevis P13602 443 49705 T290 A L T V P E L T Q Q M F D S K
Zebra Danio Brachydanio rerio NP_001019593 449 50548 T290 A L S V P E L T Q Q M F D A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24560 447 50129 T290 A L T V P E L T Q Q M F D A K
Honey Bee Apis mellifera XP_392313 447 50157 T290 A L S V P E L T Q Q M F D A K
Nematode Worm Caenorhab. elegans P41937 444 49782 T290 S L T V P E L T Q Q M F D A K
Sea Urchin Strong. purpuratus XP_791790 447 50098 T290 A L T V P E L T Q Q M F D A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.6 N.A. 80.2 N.A. 90.8 96.1 N.A. N.A. 99 98.4 95 N.A. 95.5 95.3 93 96.2
Protein Similarity: 100 94.3 N.A. 81 N.A. 95.5 98.4 N.A. N.A. 99.3 99 98 N.A. 97.7 97.9 97.9 98.4
P-Site Identity: 100 86.6 N.A. 100 N.A. 93.3 93.3 N.A. N.A. 100 100 86.6 N.A. 93.3 86.6 86.6 93.3
P-Site Similarity: 100 93.3 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 100 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 92 0 0 0 9 0 0 0 0 0 0 0 0 67 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % D
% Glu: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % K
% Leu: 0 100 0 0 0 0 100 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 92 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 100 100 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 17 0 0 0 0 0 0 0 0 0 0 34 0 % S
% Thr: 0 0 84 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _