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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC2
All Species:
40.61
Human Site:
S175
Identified Species:
68.72
UniProt:
Q13868
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13868
NP_055100.2
293
32789
S175
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Chimpanzee
Pan troglodytes
XP_001165990
285
31976
K175
P
S
L
V
K
R
Q
K
T
H
F
H
D
L
P
Rhesus Macaque
Macaca mulatta
XP_001106567
293
32714
S175
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Dog
Lupus familis
XP_850770
538
57965
S175
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV3
293
32613
S175
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Rat
Rattus norvegicus
NP_001102422
293
32671
S175
Q
G
A
L
V
Q
V
S
P
A
L
V
K
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507703
293
32690
S175
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Chicken
Gallus gallus
NP_001012816
294
32419
S176
Q
G
V
L
V
Q
V
S
P
S
L
V
K
R
Q
Frog
Xenopus laevis
NP_001085606
293
32342
S175
Q
G
L
L
V
Q
V
S
P
S
L
I
K
R
R
Zebra Danio
Brachydanio rerio
NP_001017572
254
28497
H148
K
R
Q
K
T
H
F
H
N
L
P
C
G
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611807
298
33606
F178
Q
G
I
L
V
K
V
F
P
A
L
V
K
R
R
Honey Bee
Apis mellifera
XP_396929
295
33325
S180
Q
G
I
M
L
K
V
S
P
A
L
I
K
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789513
291
32584
S172
Q
G
I
M
V
R
V
S
P
S
L
I
K
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38792
359
39409
P203
N
G
M
F
C
Q
V
P
S
S
L
I
V
R
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
98.9
52.4
N.A.
93.8
94.8
N.A.
84.6
85.3
80.8
70.3
N.A.
55.3
55.9
N.A.
62.4
Protein Similarity:
100
97.2
99.6
53.7
N.A.
98.2
97.9
N.A.
91.8
92.8
92.1
80.8
N.A.
75.5
74.9
N.A.
81.5
P-Site Identity:
100
0
100
100
N.A.
100
86.6
N.A.
100
100
80
0
N.A.
66.6
53.3
N.A.
66.6
P-Site Similarity:
100
20
100
100
N.A.
100
93.3
N.A.
100
100
100
6.6
N.A.
93.3
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
22
0
0
0
8
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
8
8
0
0
8
0
0
0
0
% F
% Gly:
0
86
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
8
0
8
0
8
0
0
0
% H
% Ile:
0
0
22
0
0
0
0
0
0
0
0
29
0
0
0
% I
% Lys:
8
0
0
8
8
15
0
8
0
0
0
0
79
0
8
% K
% Leu:
0
0
15
65
8
0
0
0
0
8
86
0
0
8
0
% L
% Met:
0
0
8
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
8
79
0
8
0
0
0
8
% P
% Gln:
79
0
8
0
0
65
8
0
0
0
0
0
0
0
50
% Q
% Arg:
0
8
0
0
0
15
0
0
0
0
0
0
0
86
22
% R
% Ser:
0
8
0
0
0
0
0
72
8
65
0
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
43
8
72
0
86
0
0
0
0
58
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _