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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUNX3 All Species: 8.79
Human Site: S54 Identified Species: 17.58
UniProt: Q13761 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13761 NP_001026850.1 415 44356 S54 R A R P E V R S M V D V L A D
Chimpanzee Pan troglodytes XP_001168112 361 38974 V13 A D H A G E L V R T D S P N F
Rhesus Macaque Macaca mulatta XP_001113682 501 52667 S137 R A R P E V R S M V D V L A D
Dog Lupus familis XP_544492 414 44288 V52 G D V P D G T V V T V M A G N
Cat Felis silvestris
Mouse Mus musculus Q64131 409 43610 S55 R T R P E V R S M V D V L A D
Rat Rattus norvegicus Q63046 450 48538 V52 R S G D R S M V E V L A D H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232978 334 36473
Frog Xenopus laevis Q6PF39 462 50351 M51 L R S T D R N M V E V L S D H
Zebra Danio Brachydanio rerio NP_571679 424 45996 V51 E S R S V V D V L A D H A G E
Tiger Blowfish Takifugu rubipres NP_001092121 407 44638 A52 R N M V D V L A D H A G E L V
Fruit Fly Dros. melanogaster Q9W349 826 84703 L275 D L L W M E R L V Q K R Q Q E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9ATN1 302 31144
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 63 48.6 N.A. 91.5 59.5 N.A. N.A. 68.9 56.9 68.1 67.9 23.3 N.A. N.A. N.A.
Protein Similarity: 100 86.9 68.2 56.1 N.A. 94.6 70.4 N.A. N.A. 74.2 69 75.2 77.3 33.1 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 6.6 N.A. 93.3 13.3 N.A. N.A. 0 0 20 13.3 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 33.3 N.A. 93.3 20 N.A. N.A. 0 20 40 26.6 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 20 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 30.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 0 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 9 0 0 0 9 0 9 9 9 17 25 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 17 0 9 25 0 9 0 9 0 42 0 9 9 25 % D
% Glu: 9 0 0 0 25 17 0 0 9 9 0 0 9 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 9 0 9 0 9 9 0 0 0 0 0 9 0 17 0 % G
% His: 0 0 9 0 0 0 0 0 0 9 0 9 0 9 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 9 9 9 0 0 0 17 9 9 0 9 9 25 9 0 % L
% Met: 0 0 9 0 9 0 9 9 25 0 0 9 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 0 0 0 0 0 9 9 % N
% Pro: 0 0 0 34 0 0 0 0 0 0 0 0 9 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 9 9 0 % Q
% Arg: 42 9 34 0 9 9 34 0 9 0 0 9 0 0 0 % R
% Ser: 0 17 9 9 0 9 0 25 0 0 0 9 9 0 0 % S
% Thr: 0 9 0 9 0 0 9 0 0 17 0 0 0 0 0 % T
% Val: 0 0 9 9 9 42 0 34 25 34 17 25 0 0 9 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _