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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
7.58
Human Site:
S380
Identified Species:
15.15
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
S380
A
G
N
L
M
N
P
S
L
G
G
Q
S
D
G
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
L327
G
N
L
M
N
P
S
L
G
G
Q
S
D
G
V
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
S466
A
G
N
L
M
N
P
S
L
G
G
Q
S
D
G
Dog
Lupus familis
XP_544492
414
44288
L380
G
N
L
M
N
P
S
L
G
G
Q
S
D
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
S375
A
G
N
L
M
N
P
S
L
G
Q
A
D
G
V
Rat
Rattus norvegicus
Q63046
450
48538
M389
A
G
S
Y
Q
F
S
M
V
G
G
E
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
L300
N
N
L
M
N
P
N
L
G
N
Q
N
D
G
V
Frog
Xenopus laevis
Q6PF39
462
50351
N427
G
S
T
L
L
N
P
N
L
P
N
Q
S
D
V
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
N384
A
G
N
T
G
N
N
N
L
I
N
A
N
L
G
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
G372
A
N
S
L
M
N
P
G
L
N
A
Q
S
E
G
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
P632
A
H
L
P
A
V
L
P
E
M
H
G
H
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
L268
R
Q
L
W
I
Y
L
L
A
P
T
L
G
A
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
66.6
26.6
N.A.
N.A.
0
46.6
40
60
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
66.6
46.6
N.A.
N.A.
6.6
60
53.3
73.3
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
0
9
0
0
0
9
0
9
17
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
34
25
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% F
% Gly:
25
42
0
0
9
0
0
9
25
50
25
9
9
34
34
% G
% His:
0
9
0
0
0
0
0
0
0
0
9
0
9
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
42
9
0
17
34
50
0
0
9
0
9
9
% L
% Met:
0
0
0
25
34
0
0
9
0
9
0
0
0
0
0
% M
% Asn:
9
34
34
0
25
50
17
17
0
17
17
9
9
0
0
% N
% Pro:
0
0
0
9
0
25
42
9
0
17
0
0
0
0
9
% P
% Gln:
0
9
0
0
9
0
0
0
0
0
34
34
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
0
9
17
0
0
0
25
25
0
0
0
17
34
17
0
% S
% Thr:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
42
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _