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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RUNX3 All Species: 11.21
Human Site: S356 Identified Species: 22.42
UniProt: Q13761 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13761 NP_001026850.1 415 44356 S356 S S S G G D R S P T R M L A S
Chimpanzee Pan troglodytes XP_001168112 361 38974 P303 S S G G D R S P T R M L A S C
Rhesus Macaque Macaca mulatta XP_001113682 501 52667 S442 S S S G G D R S P T R M L A S
Dog Lupus familis XP_544492 414 44288 S356 S S S G G E R S P T R M L A S
Cat Felis silvestris
Mouse Mus musculus Q64131 409 43610 R351 A A A G G G E R S P T R M L T
Rat Rattus norvegicus Q63046 450 48538 G365 G S S Q A Q A G P F Q T G S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232978 334 36473 E276 F S M V A G G E R S P T R M L
Frog Xenopus laevis Q6PF39 462 50351 G403 Q F S M M S G G E R S P P R I
Zebra Danio Brachydanio rerio NP_571679 424 45996 D360 G G S G S G G D R S P T R M L
Tiger Blowfish Takifugu rubipres NP_001092121 407 44638 R348 P G N T G G E R S P T R L L S
Fruit Fly Dros. melanogaster Q9W349 826 84703 Y608 V G M G M N H Y G G G Y D S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q9ATN1 302 31144 S244 A G P T T G G S M N P V R T L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.9 63 48.6 N.A. 91.5 59.5 N.A. N.A. 68.9 56.9 68.1 67.9 23.3 N.A. N.A. N.A.
Protein Similarity: 100 86.9 68.2 56.1 N.A. 94.6 70.4 N.A. N.A. 74.2 69 75.2 77.3 33.1 N.A. N.A. N.A.
P-Site Identity: 100 20 100 93.3 N.A. 13.3 20 N.A. N.A. 6.6 6.6 13.3 20 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 46.6 33.3 N.A. N.A. 13.3 6.6 20 26.6 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 20 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 30.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 9 0 17 0 9 0 0 0 0 0 9 25 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 9 17 0 9 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 9 17 9 9 0 0 0 0 0 0 % E
% Phe: 9 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % F
% Gly: 17 34 9 59 42 42 34 17 9 9 9 0 9 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 9 34 17 25 % L
% Met: 0 0 17 9 17 0 0 0 9 0 9 25 9 17 0 % M
% Asn: 0 0 9 0 0 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 9 0 9 0 0 0 0 9 34 17 25 9 9 0 9 % P
% Gln: 9 0 0 9 0 9 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 25 17 17 17 25 17 25 9 0 % R
% Ser: 34 50 50 0 9 9 9 34 17 17 9 0 0 25 34 % S
% Thr: 0 0 0 17 9 0 0 0 9 25 17 25 0 9 9 % T
% Val: 9 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _