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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
6.06
Human Site:
S220
Identified Species:
12.12
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
S220
P
S
P
R
G
S
L
S
T
T
S
H
F
S
S
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
T167
S
P
R
G
S
L
S
T
T
S
H
F
S
S
Q
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
N306
L
G
V
R
Q
Y
D
N
H
F
T
D
V
E
T
Dog
Lupus familis
XP_544492
414
44288
T220
P
S
S
P
G
G
P
T
L
P
P
E
A
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
G215
P
S
T
P
S
P
R
G
S
L
S
T
T
S
H
Rat
Rattus norvegicus
Q63046
450
48538
S229
P
R
A
S
L
N
H
S
T
A
F
N
P
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
S140
R
V
T
P
T
T
P
S
P
R
G
S
I
S
T
Frog
Xenopus laevis
Q6PF39
462
50351
A267
Y
Q
Y
L
G
S
I
A
T
Q
S
V
H
P
A
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
T224
H
Y
S
P
S
S
T
T
Q
I
P
G
L
W
P
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
P212
T
A
N
N
N
P
R
P
I
H
Q
A
H
L
S
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
V472
V
A
A
A
A
A
A
V
A
V
T
P
T
G
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
G108
G
G
A
I
S
P
F
G
N
A
A
C
A
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
26.6
N.A.
26.6
20
N.A.
N.A.
13.3
26.6
6.6
6.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
26.6
33.3
N.A.
33.3
33.3
N.A.
N.A.
26.6
46.6
13.3
13.3
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
25
9
9
9
9
9
9
17
9
9
17
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
9
9
9
9
0
0
% F
% Gly:
9
17
0
9
25
9
0
17
0
0
9
9
0
17
9
% G
% His:
9
0
0
0
0
0
9
0
9
9
9
9
17
0
9
% H
% Ile:
0
0
0
9
0
0
9
0
9
9
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
9
9
9
0
9
9
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
9
9
0
9
9
0
0
9
0
0
0
% N
% Pro:
34
9
9
34
0
25
17
9
9
9
17
9
9
9
17
% P
% Gln:
0
9
0
0
9
0
0
0
9
9
9
0
0
9
9
% Q
% Arg:
9
9
9
17
0
0
17
0
0
9
0
0
0
0
0
% R
% Ser:
9
25
17
9
34
25
9
25
9
9
25
9
9
34
25
% S
% Thr:
9
0
17
0
9
9
9
25
34
9
17
9
17
0
17
% T
% Val:
9
9
9
0
0
0
0
9
0
9
0
9
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _