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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACVR2B
All Species:
26.06
Human Site:
S479
Identified Species:
47.78
UniProt:
Q13705
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13705
NP_001097.2
512
57724
S479
G
C
V
E
E
R
V
S
L
I
R
R
S
V
N
Chimpanzee
Pan troglodytes
XP_001171684
516
58074
S483
G
C
V
E
E
R
V
S
L
I
R
R
S
V
N
Rhesus Macaque
Macaca mulatta
XP_001084713
521
58857
S488
G
C
V
E
E
R
V
S
L
I
R
R
S
V
N
Dog
Lupus familis
XP_542709
507
57202
A474
G
C
V
E
E
R
V
A
L
I
R
R
S
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P27040
536
60524
S503
G
C
V
E
E
R
V
S
L
I
R
R
S
V
N
Rat
Rattus norvegicus
P38445
513
57839
S480
G
C
V
E
E
R
V
S
L
I
R
R
S
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518896
634
71047
A602
G
E
V
G
R
G
E
A
A
E
A
S
R
A
E
Chicken
Gallus gallus
Q90670
512
57758
A479
G
C
V
E
E
R
I
A
Q
I
R
K
S
V
N
Frog
Xenopus laevis
P27041
511
57917
S478
G
C
V
E
E
R
I
S
Q
I
R
K
S
V
N
Zebra Danio
Brachydanio rerio
NP_571285
509
57460
S477
G
C
V
Q
E
R
I
S
Q
I
R
R
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395928
531
60411
A495
S
C
V
M
E
R
V
A
T
L
S
R
T
L
V
Nematode Worm
Caenorhab. elegans
P50488
744
84391
W598
G
C
A
F
A
R
V
W
N
H
I
M
S
S
P
Sea Urchin
Strong. purpuratus
XP_001194466
553
62367
A493
G
C
V
E
E
R
I
A
Q
F
S
H
S
H
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
95.9
97
N.A.
94.9
98.8
N.A.
41.6
89.4
82.8
79.3
N.A.
N.A.
51.4
25.8
49.7
Protein Similarity:
100
98.6
95.9
97.6
N.A.
94.9
99
N.A.
54.7
95.6
92.7
90
N.A.
N.A.
68.3
39.5
64
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
13.3
73.3
80
60
N.A.
N.A.
40
33.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
93.3
80
N.A.
N.A.
66.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
0
39
8
0
8
0
0
8
0
% A
% Cys:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
70
85
0
8
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
93
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% H
% Ile:
0
0
0
0
0
0
31
0
0
70
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
47
8
0
0
0
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
62
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
31
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
93
0
0
0
0
70
62
8
0
0
% R
% Ser:
8
0
0
0
0
0
0
54
0
0
16
8
77
16
8
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% T
% Val:
0
0
93
0
0
0
62
0
0
0
0
0
8
62
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _