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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53BP2
All Species:
17.88
Human Site:
Y874
Identified Species:
49.17
UniProt:
Q13625
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13625
NP_001026855.2
1128
125616
Y874
P
P
Y
P
P
P
P
Y
P
S
G
E
P
E
G
Chimpanzee
Pan troglodytes
XP_510191
1558
168185
P1309
P
S
P
V
A
E
A
P
S
P
G
E
E
Q
V
Rhesus Macaque
Macaca mulatta
XP_001093747
1412
155073
Y1158
P
P
Y
P
P
P
P
Y
P
S
G
E
P
E
G
Dog
Lupus familis
XP_547518
1263
139565
Y1000
P
P
Y
P
P
P
P
Y
P
S
G
E
P
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG79
1128
125283
Y874
P
P
Y
P
P
P
P
Y
P
S
G
E
P
E
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513723
1141
127646
Y887
P
P
Y
P
P
P
P
Y
P
S
G
E
P
E
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611565
1020
110357
M769
S
A
D
E
T
D
R
M
V
A
P
S
I
T
T
Honey Bee
Apis mellifera
XP_393703
1214
135251
V962
D
I
I
D
A
L
N
V
I
N
I
E
D
K
V
Nematode Worm
Caenorhab. elegans
Q9XVN3
769
85418
K534
A
I
E
R
R
T
V
K
G
I
L
R
R
P
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
78.6
78.2
N.A.
91
N.A.
N.A.
84.4
N.A.
N.A.
N.A.
N.A.
25
23.7
23.9
N.A.
Protein Similarity:
100
41.7
79.2
82.6
N.A.
94.3
N.A.
N.A.
89.5
N.A.
N.A.
N.A.
N.A.
42.2
39.9
39
N.A.
P-Site Identity:
100
20
100
100
N.A.
93.3
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
20
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
23
0
12
0
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
12
0
12
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
12
12
0
12
0
0
0
0
0
78
12
56
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
67
0
0
0
45
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
23
12
0
0
0
0
0
12
12
12
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
12
% N
% Pro:
67
56
12
56
56
56
56
12
56
12
12
0
56
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
12
12
0
12
0
0
0
0
12
12
0
0
% R
% Ser:
12
12
0
0
0
0
0
0
12
56
0
12
0
0
0
% S
% Thr:
0
0
0
0
12
12
0
0
0
0
0
0
0
12
12
% T
% Val:
0
0
0
12
0
0
12
12
12
0
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
56
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _