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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53BP2
All Species:
19.09
Human Site:
S726
Identified Species:
52.5
UniProt:
Q13625
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13625
NP_001026855.2
1128
125616
S726
E
A
L
R
K
K
L
S
N
A
P
R
P
L
K
Chimpanzee
Pan troglodytes
XP_510191
1558
168185
A1167
E
A
L
R
R
K
L
A
N
A
P
R
P
L
K
Rhesus Macaque
Macaca mulatta
XP_001093747
1412
155073
S1010
E
A
L
R
K
K
L
S
N
A
P
R
P
L
K
Dog
Lupus familis
XP_547518
1263
139565
S852
E
A
L
R
K
K
L
S
N
A
P
R
P
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CG79
1128
125283
S725
E
A
L
R
K
K
L
S
N
A
P
R
P
L
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513723
1141
127646
S739
E
A
L
R
K
K
L
S
N
A
P
R
P
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611565
1020
110357
A625
S
P
K
V
N
R
V
A
P
N
V
V
M
T
D
Honey Bee
Apis mellifera
XP_393703
1214
135251
E805
D
R
L
K
N
E
N
E
R
K
S
M
I
E
D
Nematode Worm
Caenorhab. elegans
Q9XVN3
769
85418
S392
R
P
T
S
F
G
D
S
L
D
E
S
R
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
78.6
78.2
N.A.
91
N.A.
N.A.
84.4
N.A.
N.A.
N.A.
N.A.
25
23.7
23.9
N.A.
Protein Similarity:
100
41.7
79.2
82.6
N.A.
94.3
N.A.
N.A.
89.5
N.A.
N.A.
N.A.
N.A.
42.2
39.9
39
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
0
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
0
0
0
0
23
0
67
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
12
0
0
12
0
0
0
0
23
% D
% Glu:
67
0
0
0
0
12
0
12
0
0
12
0
0
12
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
12
12
56
67
0
0
0
12
0
0
0
0
67
% K
% Leu:
0
0
78
0
0
0
67
0
12
0
0
0
0
78
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% M
% Asn:
0
0
0
0
23
0
12
0
67
12
0
0
0
0
0
% N
% Pro:
0
23
0
0
0
0
0
0
12
0
67
0
67
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
12
0
67
12
12
0
0
12
0
0
67
12
0
12
% R
% Ser:
12
0
0
12
0
0
0
67
0
0
12
12
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
12
0
0
12
0
0
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _