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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL2
All Species:
19.39
Human Site:
T327
Identified Species:
35.56
UniProt:
Q13617
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13617
NP_003582.2
745
86983
T327
H
D
E
G
L
R
A
T
S
N
L
T
Q
E
N
Chimpanzee
Pan troglodytes
XP_507738
829
95741
P411
R
A
V
S
T
G
L
P
H
M
I
Q
E
L
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535140
745
86988
T327
Q
D
E
G
L
R
A
T
S
N
L
T
Q
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4H8
745
86858
T327
H
D
E
G
L
R
A
T
S
N
L
T
Q
E
H
Rat
Rattus norvegicus
Q9JJ31
780
90872
T346
K
Y
V
E
Q
L
L
T
L
F
N
R
F
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508563
745
87017
T327
H
D
E
G
L
R
A
T
S
N
L
S
Q
E
N
Chicken
Gallus gallus
NP_001026141
688
80276
A252
G
E
Y
Y
K
Q
E
A
S
N
L
L
Q
E
S
Frog
Xenopus laevis
Q6GPF3
768
88937
Q324
M
S
L
Y
L
R
E
Q
G
K
A
L
V
S
E
Zebra Danio
Brachydanio rerio
XP_002666627
745
86977
T327
H
D
E
G
I
R
A
T
I
N
L
S
Q
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
T357
A
I
A
K
C
C
T
T
D
A
A
N
D
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17390
776
89707
S344
K
K
G
L
E
A
V
S
R
L
T
G
E
N
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
N325
Q
A
E
D
T
A
T
N
Q
V
A
N
T
A
S
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
S373
L
A
L
M
T
A
H
S
L
S
P
K
D
Y
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
N.A.
99.4
N.A.
97.3
28.9
N.A.
96.5
83.3
28.1
92.2
N.A.
33
N.A.
43
N.A.
Protein Similarity:
100
87.6
N.A.
99.5
N.A.
99.3
50.7
N.A.
98.6
86.4
51.5
96.9
N.A.
55.1
N.A.
64.1
N.A.
P-Site Identity:
100
0
N.A.
93.3
N.A.
93.3
6.6
N.A.
93.3
33.3
13.3
80
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
13.3
N.A.
93.3
N.A.
100
6.6
N.A.
100
53.3
13.3
93.3
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.5
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.3
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
0
0
24
39
8
0
8
24
0
0
8
0
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
0
8
0
0
0
0
8
0
0
0
16
0
0
% D
% Glu:
0
8
47
8
8
0
16
0
0
0
0
0
16
47
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
8
0
8
39
0
8
0
0
8
0
0
8
0
0
0
% G
% His:
31
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
8
0
0
0
8
0
8
0
0
0
8
% I
% Lys:
16
8
0
8
8
0
0
0
0
8
0
8
0
0
16
% K
% Leu:
8
0
16
8
39
8
16
0
16
8
47
16
0
8
0
% L
% Met:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
47
8
16
0
8
31
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% P
% Gln:
16
0
0
0
8
8
0
8
8
0
0
8
47
0
8
% Q
% Arg:
8
0
0
0
0
47
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
16
39
8
0
16
0
16
16
% S
% Thr:
0
0
0
0
24
0
16
54
0
0
8
24
8
0
0
% T
% Val:
0
0
16
0
0
0
8
0
0
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
16
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _