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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKD2
All Species:
9.09
Human Site:
T422
Identified Species:
25
UniProt:
Q13563
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13563
NP_000288.1
968
109691
T422
L
D
R
G
T
R
A
T
F
I
D
F
S
V
Y
Chimpanzee
Pan troglodytes
XP_001168415
805
91946
I336
G
A
I
P
S
W
Q
I
R
T
V
K
L
I
R
Rhesus Macaque
Macaca mulatta
XP_001099242
969
109684
T423
L
D
R
G
T
R
A
T
F
I
D
F
S
V
Y
Dog
Lupus familis
XP_544974
908
103725
T362
L
D
R
G
T
R
A
T
F
I
D
F
S
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35245
966
108978
A420
L
D
R
G
T
R
A
A
F
I
D
F
S
V
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509851
916
103775
V351
L
T
R
G
T
R
V
V
F
I
D
F
S
V
Y
Chicken
Gallus gallus
NP_001026311
881
100576
F339
T
R
A
A
F
I
D
F
S
V
Y
N
A
N
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1S7
716
80416
A247
F
V
Q
R
L
P
V
A
G
S
T
E
A
Q
S
Sea Urchin
Strong. purpuratus
NP_999827
907
103454
L358
L
D
R
G
T
R
A
L
F
V
D
F
T
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43
98.4
88
N.A.
90.2
N.A.
N.A.
40
74.6
N.A.
N.A.
N.A.
N.A.
N.A.
29.8
48.6
Protein Similarity:
100
60.3
98.9
90.5
N.A.
93.8
N.A.
N.A.
56.4
83.3
N.A.
N.A.
N.A.
N.A.
N.A.
46.2
64.9
P-Site Identity:
100
0
100
100
N.A.
93.3
N.A.
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
N.A.
0
80
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
N.A.
N.A.
80
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
0
0
56
23
0
0
0
0
23
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
56
0
0
0
0
12
0
0
0
67
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
12
0
0
0
12
0
0
12
67
0
0
67
0
0
0
% F
% Gly:
12
0
0
67
0
0
0
0
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
12
0
12
0
56
0
0
0
12
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% K
% Leu:
67
0
0
0
12
0
0
12
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% N
% Pro:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
12
0
0
0
0
0
0
12
0
% Q
% Arg:
0
12
67
12
0
67
0
0
12
0
0
0
0
0
12
% R
% Ser:
0
0
0
0
12
0
0
0
12
12
0
0
56
0
12
% S
% Thr:
12
12
0
0
67
0
0
34
0
12
12
0
12
0
0
% T
% Val:
0
12
0
0
0
0
23
12
0
23
12
0
0
67
0
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
67
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _