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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 11.82
Human Site: T748 Identified Species: 23.64
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 T748 F C R N L K A T S Q H E C S S
Chimpanzee Pan troglodytes XP_516792 2646 301618 T750 F C R N L K A T S Q H E C S S
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 T748 F C R N L K A T S Q H E C S S
Dog Lupus familis XP_534295 2644 301635 A751 F C K N L K V A S Q H E C S S
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 H751 N L K A T S Q H E C S S S Q V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 T763 L C S S L T V T A L P S S K L
Zebra Danio Brachydanio rerio XP_696163 2643 299171 S755 L S I S D F H S S Q T S S I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 E737 I A H M E D N E I W L F H W F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 C777 H R A V Q L R C T T C T P G H
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 D745 E K H G K T T D Y L Q G F W C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 N754 N L Q S L Y F N L L Y D E S S
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 Q616 A T L I K F L Q S Q K L P V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 100 100 80 N.A. 0 N.A. N.A. N.A. N.A. 20 13.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 6.6 N.A. N.A. N.A. N.A. 33.3 26.6 N.A. 0 N.A. N.A. 6.6
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 0 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 0 N.A. N.A. 46.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 9 9 0 0 25 9 9 0 0 0 0 0 0 % A
% Cys: 0 42 0 0 0 0 0 9 0 9 9 0 34 0 9 % C
% Asp: 0 0 0 0 9 9 0 9 0 0 0 9 0 0 0 % D
% Glu: 9 0 0 0 9 0 0 9 9 0 0 34 9 0 0 % E
% Phe: 34 0 0 0 0 17 9 0 0 0 0 9 9 0 9 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 9 0 9 9 % G
% His: 9 0 17 0 0 0 9 9 0 0 34 0 9 0 9 % H
% Ile: 9 0 9 9 0 0 0 0 9 0 0 0 0 9 0 % I
% Lys: 0 9 17 0 17 34 0 0 0 0 9 0 0 9 0 % K
% Leu: 17 17 9 0 50 9 9 0 9 25 9 9 0 0 9 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 34 0 0 9 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 17 0 0 % P
% Gln: 0 0 9 0 9 0 9 9 0 50 9 0 0 9 0 % Q
% Arg: 0 9 25 0 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 9 25 0 9 0 9 50 0 9 25 25 42 42 % S
% Thr: 0 9 0 0 9 17 9 34 9 9 9 9 0 0 0 % T
% Val: 0 0 0 9 0 0 17 0 0 0 0 0 0 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 17 0 % W
% Tyr: 0 0 0 0 0 9 0 0 9 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _