Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 33.03
Human Site: T1176 Identified Species: 66.06
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 T1176 S V R V K M M T T L R T G L R
Chimpanzee Pan troglodytes XP_516792 2646 301618 T1178 S V R V K M M T T L R T G L R
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 T1176 S V R V K M M T T L R T G L R
Dog Lupus familis XP_534295 2644 301635 T1179 S V R V K M M T T L R T G L R
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 T1176 S V R V K M M T T L R T G L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 T1191 S V R V K M M T T L R T G L R
Zebra Danio Brachydanio rerio XP_696163 2643 299171 T1179 S V R V K M M T T L R T G L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 P1128 A E E E N Q S P P L V D Q L R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 T1191 G V R V K V M T T L K I G L R
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 L1185 Y V P K L M V L L M H A I D K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 L1160 A L Q S E G L L V L H F F T R
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 S1000 D T L I K E K S D L I L K L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 100 N.A. 20 N.A. N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 100 N.A. 26.6 N.A. N.A. 86.6
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 20 N.A.
P-Site Similarity: 33.3 N.A. N.A. 46.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 9 0 0 9 0 9 0 % D
% Glu: 0 9 9 9 9 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % F
% Gly: 9 0 0 0 0 9 0 0 0 0 0 0 67 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 9 9 9 0 0 % I
% Lys: 0 0 0 9 75 0 9 0 0 0 9 0 9 0 17 % K
% Leu: 0 9 9 0 9 0 9 17 9 92 0 9 0 84 0 % L
% Met: 0 0 0 0 0 67 67 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 0 0 0 0 9 9 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 67 0 0 0 0 0 0 0 59 0 0 0 84 % R
% Ser: 59 0 0 9 0 0 9 9 0 0 0 0 0 0 0 % S
% Thr: 0 9 0 0 0 0 0 67 67 0 0 59 0 9 0 % T
% Val: 0 75 0 67 0 9 9 0 9 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _