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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 22.42
Human Site: S603 Identified Species: 44.85
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 S603 L P W I Y S H S D D G C L K L
Chimpanzee Pan troglodytes XP_516792 2646 301618 S605 L P W I Y S H S D D G C L K L
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 S603 L P W I Y S H S D D G C L K L
Dog Lupus familis XP_534295 2644 301635 S606 L P W I H S H S D D G S L K L
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 S606 L P W I Y S Y S D D N S L K M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 S618 L P W L Q N H S N H A S F K V
Zebra Danio Brachydanio rerio XP_696163 2643 299171 S608 V P W V L E H S S Q S V Y Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 K589 P G K L S V F K V K D R I E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 G629 R T L Q L L A G A G Q S G G A
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 F596 M E D K P F K F K G D S T D L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 G602 V G I W T K L G L Q D G S D F
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 K472 L A C L E S E K F S G T L P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 100 100 86.6 N.A. 73.3 N.A. N.A. N.A. N.A. 40 26.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 N.A. N.A. N.A. N.A. 66.6 46.6 N.A. 26.6 N.A. N.A. 0
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 26.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 9 0 9 0 9 0 0 0 9 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 25 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 42 42 25 0 0 17 0 % D
% Glu: 0 9 0 0 9 9 9 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 9 9 9 9 0 0 0 9 0 9 % F
% Gly: 0 17 0 0 0 0 0 17 0 17 42 9 9 9 0 % G
% His: 0 0 0 0 9 0 50 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 9 42 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 9 9 0 9 9 17 9 9 0 0 0 50 0 % K
% Leu: 59 0 9 25 17 9 9 0 9 0 0 0 50 0 50 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 9 0 0 9 0 9 0 0 0 9 % N
% Pro: 9 59 0 0 9 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 9 9 0 0 0 0 17 9 0 0 9 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 9 50 0 59 9 9 9 42 9 0 0 % S
% Thr: 0 9 0 0 9 0 0 0 0 0 0 9 9 0 9 % T
% Val: 17 0 0 9 0 9 0 0 9 0 0 9 0 0 9 % V
% Trp: 0 0 59 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 0 9 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _