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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 17.27
Human Site: S553 Identified Species: 34.55
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 S553 S C R S L L E S V Q K L D L E
Chimpanzee Pan troglodytes XP_516792 2646 301618 S555 S C R S L L E S V Q K P D L E
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 T553 S C R S L L E T V Q K P D L E
Dog Lupus familis XP_534295 2644 301635 S556 S C R S L L E S V Q K P D L E
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 S556 S C R S L L E S V Q K L E L E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 A568 C R K V L D S A H Q R A N I N
Zebra Danio Brachydanio rerio XP_696163 2643 299171 H558 A N N Y N E E H L E H L V E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 F539 S E E T Q E I F C S N L P Q L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 A579 K T H S L K K A P R G E R R S
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 F546 T Y L S I C I F Q Q M H A W I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 D552 N L L L V G V D P Q Y E Y T S
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 P422 Y R V N Q L S P G F F Q R A G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 93.3 86.6 93.3 N.A. 93.3 N.A. N.A. N.A. N.A. 13.3 13.3 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 100 N.A. N.A. N.A. N.A. 46.6 33.3 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 17 0 0 0 9 9 9 0 % A
% Cys: 9 42 0 0 0 9 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 0 0 0 0 34 0 0 % D
% Glu: 0 9 9 0 0 17 50 0 0 9 0 17 9 9 42 % E
% Phe: 0 0 0 0 0 0 0 17 0 9 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 9 0 9 0 0 0 17 % G
% His: 0 0 9 0 0 0 0 9 9 0 9 9 0 0 0 % H
% Ile: 0 0 0 0 9 0 17 0 0 0 0 0 0 9 9 % I
% Lys: 9 0 9 0 0 9 9 0 0 0 42 0 0 0 0 % K
% Leu: 0 9 17 9 59 50 0 0 9 0 0 34 0 42 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 9 9 9 9 9 0 0 0 0 0 9 0 9 0 9 % N
% Pro: 0 0 0 0 0 0 0 9 17 0 0 25 9 0 0 % P
% Gln: 0 0 0 0 17 0 0 0 9 67 0 9 0 9 0 % Q
% Arg: 0 17 42 0 0 0 0 0 0 9 9 0 17 9 0 % R
% Ser: 50 0 0 59 0 0 17 34 0 9 0 0 0 0 17 % S
% Thr: 9 9 0 9 0 0 0 9 0 0 0 0 0 9 0 % T
% Val: 0 0 9 9 9 0 9 0 42 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 9 9 0 9 0 0 0 0 0 0 9 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _