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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATR All Species: 12.73
Human Site: S529 Identified Species: 25.45
UniProt: Q13535 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13535 NP_001175.2 2644 301367 S529 H K S K K K P S V V I T W M S
Chimpanzee Pan troglodytes XP_516792 2646 301618 S531 H K S K K K P S V V I T W M S
Rhesus Macaque Macaca mulatta XP_001112149 2644 301431 S529 H K S K K K P S V V I T W M S
Dog Lupus familis XP_534295 2644 301635 S532 Q K C K K K P S V E I T W M S
Cat Felis silvestris
Mouse Mus musculus Q9JKK8 2635 300205 P532 H K Y K K K P P V V V T W M S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q9DE14 2654 301441 P544 I Q S V E I V P H V F W L S P
Zebra Danio Brachydanio rerio XP_696163 2643 299171 L534 V V A Q L I W L K P Q M L A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXG8 2517 289311 H515 L E T P S S V H T Q M Q S F Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786094 2665 299705 G555 T R S C C R F G E D F R N L S
Poplar Tree Populus trichocarpa XP_002305538 2740 307311 A522 D S L R P D V A L A A L S M L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FKS4 2702 302347 E528 W I A G Q V E E T N P I M F D
Baker's Yeast Sacchar. cerevisiae P38111 2368 273324 L398 K Q L E K L R L L V L K K F N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.7 94.9 N.A. 90.4 N.A. N.A. N.A. N.A. 72.8 65.3 N.A. 26.1 N.A. N.A. 43
Protein Similarity: 100 99.1 99.5 97.2 N.A. 95.1 N.A. N.A. N.A. N.A. 83.5 78.5 N.A. 47.6 N.A. N.A. 60.8
P-Site Identity: 100 100 100 80 N.A. 80 N.A. N.A. N.A. N.A. 13.3 0 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 80 N.A. 86.6 N.A. N.A. N.A. N.A. 26.6 13.3 N.A. 20 N.A. N.A. 33.3
Percent
Protein Identity: 27 N.A. N.A. 26.5 21.9 N.A.
Protein Similarity: 46 N.A. N.A. 46.1 41.7 N.A.
P-Site Identity: 6.6 N.A. N.A. 0 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 0 0 9 0 9 9 0 0 9 0 % A
% Cys: 0 0 9 9 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 9 0 0 0 9 0 0 0 0 9 % D
% Glu: 0 9 0 9 9 0 9 9 9 9 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 17 0 0 25 0 % F
% Gly: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 34 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 0 17 0 0 0 0 34 9 0 0 0 % I
% Lys: 9 42 0 42 50 42 0 0 9 0 0 9 9 0 0 % K
% Leu: 9 0 17 0 9 9 0 17 17 0 9 9 17 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 9 9 50 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 9 % N
% Pro: 0 0 0 9 9 0 42 17 0 9 9 0 0 0 9 % P
% Gln: 9 17 0 9 9 0 0 0 0 9 9 9 0 0 9 % Q
% Arg: 0 9 0 9 0 9 9 0 0 0 0 9 0 0 0 % R
% Ser: 0 9 42 0 9 9 0 34 0 0 0 0 17 9 50 % S
% Thr: 9 0 9 0 0 0 0 0 17 0 0 42 0 0 0 % T
% Val: 9 9 0 9 0 9 25 0 42 50 9 0 0 0 0 % V
% Trp: 9 0 0 0 0 0 9 0 0 0 0 9 42 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _