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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AQP6
All Species:
11.82
Human Site:
T129
Identified Species:
23.64
UniProt:
Q13520
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13520
NP_001643.2
282
29370
T129
M
P
G
D
I
R
E
T
L
G
I
N
V
V
R
Chimpanzee
Pan troglodytes
XP_001157230
282
29322
T129
M
P
G
D
I
R
E
T
L
G
I
N
V
V
R
Rhesus Macaque
Macaca mulatta
XP_001110572
271
28897
L121
G
D
L
A
V
N
A
L
S
N
S
T
T
A
G
Dog
Lupus familis
XP_850452
271
28631
M121
R
E
T
L
G
V
N
M
V
R
S
S
T
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4A0
293
30690
T126
T
P
G
G
I
R
E
T
L
G
V
N
V
V
H
Rat
Rattus norvegicus
Q9WTY0
276
28841
T126
T
P
G
G
V
R
E
T
L
G
V
N
V
V
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518393
255
27145
L105
G
N
L
A
I
N
K
L
S
N
N
T
T
S
G
Chicken
Gallus gallus
P28238
262
27053
V112
Y
G
V
T
P
A
A
V
R
G
T
L
G
L
S
Frog
Xenopus laevis
NP_001079331
273
29418
A121
R
G
N
L
A
I
N
A
I
N
S
G
S
P
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5Z7
245
25557
A94
G
E
I
S
I
L
K
A
A
F
Y
I
I
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q84RL6
248
25114
I98
A
V
G
G
H
I
T
I
L
T
G
I
L
Y
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVX8
278
29482
C124
V
A
Y
M
V
A
Q
C
L
G
A
I
C
G
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
54.6
76.5
N.A.
71.6
76.9
N.A.
50.3
46
51.7
N.A.
N.A.
36.1
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
66.6
85.1
N.A.
78.5
84
N.A.
59.9
59.9
67
N.A.
N.A.
49.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
73.3
66.6
N.A.
6.6
6.6
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
13.3
N.A.
80
80
N.A.
13.3
13.3
6.6
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
32.2
N.A.
37.9
N.A.
N.A.
Protein Similarity:
N.A.
47.8
N.A.
52.1
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
9
17
17
17
9
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
17
0
0
0
0
34
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
25
17
42
25
9
0
0
0
0
50
9
9
9
9
25
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
9
0
42
17
0
9
9
0
17
25
9
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
17
17
0
9
0
17
50
0
0
9
9
9
0
% L
% Met:
17
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
17
17
0
0
25
9
34
0
0
0
% N
% Pro:
0
34
0
0
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
17
0
0
0
0
34
0
0
9
9
0
0
0
0
17
% R
% Ser:
0
0
0
9
0
0
0
0
17
0
25
9
9
17
9
% S
% Thr:
17
0
9
9
0
0
9
34
0
9
9
17
25
0
9
% T
% Val:
9
9
9
0
25
9
0
9
9
0
17
0
34
42
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _