KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBB3
All Species:
40.91
Human Site:
T72
Identified Species:
90
UniProt:
Q13509
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13509
NP_006077.2
450
50433
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Chimpanzee
Pan troglodytes
Q8WP14
444
49773
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860049
456
51071
V72
Y
V
P
R
A
I
L
V
D
L
E
P
G
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERD7
450
50400
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Rat
Rattus norvegicus
Q6P9T8
445
49782
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P09652
449
50402
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Frog
Xenopus laevis
P30883
445
49797
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24560
447
50129
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Honey Bee
Apis mellifera
XP_392313
447
50157
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
S
G
Nematode Worm
Caenorhab. elegans
P41937
444
49782
T72
L
V
D
L
E
P
G
T
M
D
S
V
R
A
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P18025
446
49944
T72
L
M
D
L
E
P
G
T
M
D
S
V
R
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
N.A.
98.6
N.A.
99.7
91.5
N.A.
N.A.
99.3
91.7
N.A.
N.A.
90.4
90.6
88.6
N.A.
Protein Similarity:
100
91.5
N.A.
98.6
N.A.
100
95.3
N.A.
N.A.
99.3
95.5
N.A.
N.A.
95.1
95.5
94.8
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
100
N.A.
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
Percent
Protein Identity:
N.A.
82.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
91.3
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
91
0
0
0
0
0
10
91
0
0
0
0
0
% D
% Glu:
0
0
0
0
91
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
91
0
0
0
0
0
10
0
91
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
91
0
0
91
0
0
10
0
0
10
0
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
91
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
91
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
91
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
91
0
0
82
0
% S
% Thr:
0
0
0
0
0
0
0
91
0
0
0
0
0
10
0
% T
% Val:
0
91
0
0
0
0
0
10
0
0
0
91
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _