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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX1
All Species:
6.97
Human Site:
Y232
Identified Species:
13.94
UniProt:
Q13505
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13505
NP_002446.2
466
51477
Y232
K
E
K
Y
N
A
D
Y
D
L
S
A
R
Q
G
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
Q88
D
Y
E
L
S
A
K
Q
G
A
D
T
L
A
Y
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
K85
A
D
Y
E
L
S
A
K
Q
G
A
D
T
L
A
Dog
Lupus familis
XP_537253
462
50359
Y228
K
E
K
Y
N
A
D
Y
D
L
S
A
R
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
T93
S
A
R
Q
G
A
D
T
L
A
F
M
S
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
K75
Y
V
A
L
L
E
E
K
L
L
P
A
V
L
H
Chicken
Gallus gallus
NP_001072951
247
27799
S23
L
P
S
L
H
P
E
S
L
T
V
M
A
Y
A
Frog
Xenopus laevis
Q3KPT9
309
34626
K84
A
D
Y
V
L
S
A
K
E
G
S
D
T
L
A
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
G89
F
E
L
T
A
K
Q
G
A
D
T
M
A
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624291
292
33701
I68
T
F
N
A
V
K
D
I
I
E
F
F
R
K
E
Nematode Worm
Caenorhab. elegans
O45503
312
35301
I88
I
D
A
D
L
T
T
I
E
K
A
Q
L
D
A
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
Y95
Q
R
A
D
I
L
A
Y
S
S
L
L
E
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.8
29.8
79.8
N.A.
62
N.A.
N.A.
27
28.3
31.7
30
N.A.
N.A.
25.9
24.8
29.1
Protein Similarity:
100
44.2
44.2
84.5
N.A.
64.5
N.A.
N.A.
39
39.4
42.7
42.2
N.A.
N.A.
38.8
36.4
43.3
P-Site Identity:
100
6.6
0
100
N.A.
13.3
N.A.
N.A.
13.3
0
6.6
6.6
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
100
20
20
100
N.A.
20
N.A.
N.A.
20
13.3
26.6
13.3
N.A.
N.A.
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
25
9
9
34
25
0
9
17
17
25
17
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
25
0
17
0
0
34
0
17
9
9
17
0
9
0
% D
% Glu:
0
25
9
9
0
9
17
0
17
9
0
0
9
9
9
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
17
9
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
9
17
0
0
0
0
17
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
9
0
0
0
9
0
0
17
9
0
0
0
0
0
9
% I
% Lys:
17
0
17
0
0
17
9
25
0
9
0
0
0
9
9
% K
% Leu:
9
0
9
25
34
9
0
0
25
25
9
9
17
34
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% M
% Asn:
0
0
9
0
17
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% P
% Gln:
9
0
0
9
0
0
9
9
9
0
0
9
0
17
0
% Q
% Arg:
0
9
9
0
0
0
0
0
0
0
0
0
25
0
0
% R
% Ser:
9
0
9
0
9
17
0
9
9
9
25
0
9
0
0
% S
% Thr:
9
0
0
9
0
9
9
9
0
9
9
9
17
0
0
% T
% Val:
0
9
0
9
9
0
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
17
17
0
0
0
25
0
0
0
0
0
17
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _