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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTX1
All Species:
4.85
Human Site:
T447
Identified Species:
9.7
UniProt:
Q13505
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13505
NP_002446.2
466
51477
T447
I
V
S
I
Q
R
A
T
P
A
R
A
P
G
T
Chimpanzee
Pan troglodytes
XP_001137204
312
35075
K296
P
R
K
L
P
T
L
K
L
T
P
A
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001104637
310
34847
K294
P
R
K
L
P
T
L
K
L
T
P
A
E
E
E
Dog
Lupus familis
XP_537253
462
50359
T443
I
V
S
I
Q
R
A
T
P
A
R
A
P
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P47802
317
35605
R301
I
Q
R
T
S
P
A
R
A
P
G
T
R
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510944
299
33244
K283
H
R
K
I
P
A
L
K
L
T
P
A
A
A
E
Chicken
Gallus gallus
NP_001072951
247
27799
F231
Q
L
T
N
L
C
R
F
C
D
D
I
L
T
C
Frog
Xenopus laevis
Q3KPT9
309
34626
K293
P
Q
K
L
S
T
L
K
P
V
G
G
A
E
N
Zebra Danio
Brachydanio rerio
Q4VBW0
313
35209
H297
P
Q
H
R
P
H
R
H
E
A
K
P
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624291
292
33701
T276
Q
L
L
A
G
L
F
T
T
L
I
M
A
T
Y
Nematode Worm
Caenorhab. elegans
O45503
312
35301
A296
L
T
L
S
L
V
F
A
I
H
T
G
L
I
Q
Sea Urchin
Strong. purpuratus
XP_790728
319
36709
D303
I
V
D
D
D
E
M
D
D
H
G
M
M
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.8
29.8
79.8
N.A.
62
N.A.
N.A.
27
28.3
31.7
30
N.A.
N.A.
25.9
24.8
29.1
Protein Similarity:
100
44.2
44.2
84.5
N.A.
64.5
N.A.
N.A.
39
39.4
42.7
42.2
N.A.
N.A.
38.8
36.4
43.3
P-Site Identity:
100
6.6
6.6
93.3
N.A.
13.3
N.A.
N.A.
13.3
0
6.6
6.6
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
13.3
N.A.
N.A.
13.3
13.3
13.3
13.3
N.A.
N.A.
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
25
9
9
25
0
42
25
25
0
% A
% Cys:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
9
% C
% Asp:
0
0
9
9
9
0
0
9
9
9
9
0
0
9
9
% D
% Glu:
0
0
0
0
0
9
0
0
9
0
0
0
17
25
25
% E
% Phe:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
25
17
0
9
0
% G
% His:
9
0
9
0
0
9
0
9
0
17
0
0
0
0
0
% H
% Ile:
34
0
0
25
0
0
0
0
9
0
9
9
0
9
0
% I
% Lys:
0
0
34
0
0
0
0
34
0
0
9
0
0
0
0
% K
% Leu:
9
17
17
25
17
9
34
0
25
9
0
0
17
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
17
9
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
34
0
0
0
34
9
0
0
25
9
25
9
17
0
9
% P
% Gln:
17
25
0
0
17
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
25
9
9
0
17
17
9
0
0
17
0
9
0
0
% R
% Ser:
0
0
17
9
17
0
0
0
0
0
0
0
9
9
0
% S
% Thr:
0
9
9
9
0
25
0
25
9
25
9
9
0
17
17
% T
% Val:
0
25
0
0
0
9
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _