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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTM1
All Species:
25.76
Human Site:
Y277
Identified Species:
47.22
UniProt:
Q13496
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13496
NP_000243.1
603
69932
Y277
Q
I
S
K
L
T
I
Y
D
A
R
P
S
V
N
Chimpanzee
Pan troglodytes
XP_001146719
676
76956
F352
Q
S
H
K
I
F
I
F
D
A
R
P
S
V
N
Rhesus Macaque
Macaca mulatta
XP_001091072
603
69889
Y277
Q
I
S
K
L
T
I
Y
D
A
R
P
S
V
N
Dog
Lupus familis
XP_855209
603
69932
Y277
Q
I
S
K
L
T
I
Y
D
A
R
P
N
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2C5
603
69576
Y277
Q
T
S
K
L
M
I
Y
D
A
R
P
S
V
N
Rat
Rattus norvegicus
Q6AXQ4
602
69333
Y277
Q
T
S
K
L
T
I
Y
D
A
R
P
G
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508837
602
69798
Y277
Q
I
S
K
L
T
I
Y
D
A
R
P
N
V
N
Chicken
Gallus gallus
Q5ZIV1
571
65950
V256
A
R
P
S
V
N
A
V
A
N
K
A
K
G
G
Frog
Xenopus laevis
Q52KU6
602
69712
Y276
Q
T
S
K
L
T
I
Y
D
A
R
P
N
V
N
Zebra Danio
Brachydanio rerio
A0JMK5
620
71091
F295
Q
S
H
K
L
F
I
F
D
A
R
P
S
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22712
1006
113596
Q362
I
E
G
E
E
K
K
Q
F
I
I
M
D
A
R
Sea Urchin
Strong. purpuratus
XP_788958
678
77013
M352
Q
S
H
K
L
V
I
M
D
A
R
P
T
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47147
688
80133
K273
N
K
D
I
R
R
T
K
H
V
I
V
D
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
99.5
96.1
N.A.
91.8
80.5
N.A.
86.4
61.8
79.5
57.9
N.A.
N.A.
N.A.
21
52.2
Protein Similarity:
100
72.3
99.6
98.6
N.A.
96.8
92.2
N.A.
94.3
76.7
90.3
75.3
N.A.
N.A.
N.A.
37.5
69.3
P-Site Identity:
100
66.6
100
93.3
N.A.
86.6
86.6
N.A.
93.3
0
86.6
73.3
N.A.
N.A.
N.A.
0
66.6
P-Site Similarity:
100
80
100
100
N.A.
86.6
86.6
N.A.
100
13.3
93.3
80
N.A.
N.A.
N.A.
6.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
8
77
0
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
77
0
0
0
16
0
0
% D
% Glu:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
16
0
16
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
8
% G
% His:
0
0
24
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
31
0
8
8
0
77
0
0
8
16
0
0
0
0
% I
% Lys:
0
8
0
77
0
8
8
8
0
0
8
0
8
0
0
% K
% Leu:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
8
0
0
24
0
77
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
77
0
0
0
% P
% Gln:
77
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
8
8
0
0
0
0
77
0
0
0
16
% R
% Ser:
0
24
54
8
0
0
0
0
0
0
0
0
39
0
0
% S
% Thr:
0
24
0
0
0
47
8
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
8
8
0
8
0
8
0
8
0
77
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _