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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTM1
All Species:
31.21
Human Site:
T218
Identified Species:
57.22
UniProt:
Q13496
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13496
NP_000243.1
603
69932
T218
D
D
L
R
R
V
A
T
F
R
S
R
N
R
I
Chimpanzee
Pan troglodytes
XP_001146719
676
76956
S293
E
E
L
K
R
V
A
S
F
R
S
R
G
R
I
Rhesus Macaque
Macaca mulatta
XP_001091072
603
69889
T218
D
D
L
R
R
V
A
T
F
R
S
R
N
R
I
Dog
Lupus familis
XP_855209
603
69932
T218
D
D
L
R
R
V
A
T
F
R
S
R
N
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2C5
603
69576
T218
D
D
L
R
R
I
A
T
F
R
S
R
N
R
L
Rat
Rattus norvegicus
Q6AXQ4
602
69333
T218
D
D
L
R
R
V
A
T
F
R
S
R
N
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508837
602
69798
S218
D
D
L
R
K
V
A
S
F
R
S
R
S
R
I
Chicken
Gallus gallus
Q5ZIV1
571
65950
V197
R
S
R
G
R
I
P
V
L
S
W
I
H
P
E
Frog
Xenopus laevis
Q52KU6
602
69712
A217
E
D
L
K
R
V
A
A
F
R
S
R
N
R
I
Zebra Danio
Brachydanio rerio
A0JMK5
620
71091
S236
D
E
L
R
R
V
S
S
F
R
A
K
G
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22712
1006
113596
P303
D
D
I
R
K
G
A
P
Y
R
S
I
G
R
F
Sea Urchin
Strong. purpuratus
XP_788958
678
77013
A293
E
L
L
R
Q
V
A
A
F
R
S
R
N
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47147
688
80133
K214
I
L
L
K
H
A
S
K
F
R
S
Q
K
R
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
99.5
96.1
N.A.
91.8
80.5
N.A.
86.4
61.8
79.5
57.9
N.A.
N.A.
N.A.
21
52.2
Protein Similarity:
100
72.3
99.6
98.6
N.A.
96.8
92.2
N.A.
94.3
76.7
90.3
75.3
N.A.
N.A.
N.A.
37.5
69.3
P-Site Identity:
100
66.6
100
100
N.A.
86.6
100
N.A.
80
6.6
80
60
N.A.
N.A.
N.A.
46.6
66.6
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
100
20
93.3
93.3
N.A.
N.A.
N.A.
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
77
16
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
85
0
0
0
0
0
8
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
0
24
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
0
0
16
0
0
0
0
0
16
0
0
70
% I
% Lys:
0
0
0
24
16
0
0
8
0
0
0
8
8
0
0
% K
% Leu:
0
16
85
0
0
0
0
0
8
0
0
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
8
70
70
0
0
0
0
93
0
70
0
93
0
% R
% Ser:
0
8
0
0
0
0
16
24
0
8
85
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
70
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _