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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD5
All Species:
18.18
Human Site:
Y307
Identified Species:
36.36
UniProt:
Q13467
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13467
NP_003459.2
585
64507
Y307
R
E
H
N
H
I
H
Y
E
T
T
G
P
A
L
Chimpanzee
Pan troglodytes
XP_526008
585
64475
Y307
R
E
H
N
H
I
H
Y
E
T
T
G
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001096837
635
68033
G349
G
G
A
P
G
A
G
G
A
G
G
A
G
G
A
Dog
Lupus familis
XP_545614
589
64543
Y307
R
E
H
S
H
I
H
Y
E
T
T
G
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQD0
585
64119
Y307
R
E
H
S
H
I
H
Y
E
T
T
G
P
A
L
Rat
Rattus norvegicus
Q8CHL0
585
64093
Y307
R
E
H
S
H
I
H
Y
E
T
T
G
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA06
523
59263
V248
L
S
G
C
Y
T
M
V
S
V
A
Y
I
A
G
Frog
Xenopus laevis
P58421
559
63500
A284
I
V
G
H
E
N
V
A
C
N
K
D
H
I
H
Zebra Danio
Brachydanio rerio
NP_571209
592
66471
I317
G
T
G
D
Q
Q
H
I
L
Y
D
T
T
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
S389
G
L
L
L
R
E
S
S
T
G
P
H
S
C
T
Honey Bee
Apis mellifera
XP_397259
711
74000
A410
G
S
A
L
K
S
R
A
Q
G
P
E
A
C
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188449
555
62346
G280
C
Y
F
M
V
A
L
G
F
I
I
R
L
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
60.9
96.2
N.A.
96.2
96.4
N.A.
N.A.
45.2
73.3
71.1
N.A.
50.8
48.9
N.A.
61.3
Protein Similarity:
100
99.6
69.1
96.7
N.A.
97.2
97.6
N.A.
N.A.
58.9
81.1
78.5
N.A.
60.9
60.2
N.A.
72.3
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
0
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
13.3
6.6
13.3
N.A.
0
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
17
0
17
9
0
9
9
9
50
9
% A
% Cys:
9
0
0
9
0
0
0
0
9
0
0
0
0
17
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
42
0
0
9
9
0
0
42
0
0
9
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
34
9
25
0
9
0
9
17
0
25
9
42
9
17
9
% G
% His:
0
0
42
9
42
0
50
0
0
0
0
9
9
0
9
% H
% Ile:
9
0
0
0
0
42
0
9
0
9
9
0
9
9
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
9
9
9
17
0
0
9
0
9
0
0
0
9
0
42
% L
% Met:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
9
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
17
0
42
0
9
% P
% Gln:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
42
0
0
0
9
0
9
0
0
0
0
9
0
0
0
% R
% Ser:
0
17
0
25
0
9
9
9
9
0
0
0
9
0
0
% S
% Thr:
0
9
0
0
0
9
0
0
9
42
42
9
9
0
9
% T
% Val:
0
9
0
0
9
0
9
9
0
9
0
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
0
0
42
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _