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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD5
All Species:
17.27
Human Site:
Y223
Identified Species:
34.55
UniProt:
Q13467
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13467
NP_003459.2
585
64507
Y223
P
N
C
A
V
P
C
Y
Q
P
S
F
S
A
D
Chimpanzee
Pan troglodytes
XP_526008
585
64475
Y223
P
N
C
A
V
P
C
Y
Q
P
S
F
S
A
D
Rhesus Macaque
Macaca mulatta
XP_001096837
635
68033
H265
A
N
C
A
L
P
C
H
N
P
F
F
S
Q
D
Dog
Lupus familis
XP_545614
589
64543
Y223
P
N
C
A
V
P
C
Y
Q
P
S
F
S
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQD0
585
64119
Y223
P
N
C
A
V
P
C
Y
Q
P
S
F
S
P
D
Rat
Rattus norvegicus
Q8CHL0
585
64093
Y223
P
N
C
A
V
P
C
Y
Q
P
S
F
S
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA06
523
59263
K164
F
H
C
P
R
A
L
K
V
P
G
Y
L
N
Y
Frog
Xenopus laevis
P58421
559
63500
G200
L
Y
N
R
I
K
T
G
Q
V
P
N
C
A
M
Zebra Danio
Brachydanio rerio
NP_571209
592
66471
H233
P
N
C
A
L
P
C
H
Q
P
Y
F
S
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
K305
P
N
C
G
I
P
C
K
G
P
F
F
S
N
D
Honey Bee
Apis mellifera
XP_397259
711
74000
H326
P
N
C
A
L
P
C
H
G
A
F
L
T
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188449
555
62346
V196
C
N
A
P
L
I
S
V
P
E
T
H
P
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
60.9
96.2
N.A.
96.2
96.4
N.A.
N.A.
45.2
73.3
71.1
N.A.
50.8
48.9
N.A.
61.3
Protein Similarity:
100
99.6
69.1
96.7
N.A.
97.2
97.6
N.A.
N.A.
58.9
81.1
78.5
N.A.
60.9
60.2
N.A.
72.3
P-Site Identity:
100
100
60
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
73.3
N.A.
60
40
N.A.
6.6
P-Site Similarity:
100
100
73.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
26.6
20
86.6
N.A.
66.6
73.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
67
0
9
0
0
0
9
0
0
0
25
0
% A
% Cys:
9
0
84
0
0
0
75
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
25
67
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
9
17
0
9
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
25
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
17
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
17
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
0
34
0
9
0
0
0
0
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
84
9
0
0
0
0
0
9
0
0
9
0
17
0
% N
% Pro:
67
0
0
17
0
75
0
0
9
75
9
0
9
25
0
% P
% Gln:
0
0
0
0
0
0
0
0
59
0
0
0
0
17
0
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
0
42
0
67
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% T
% Val:
0
0
0
0
42
0
0
9
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
42
0
0
9
9
0
9
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _