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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD5
All Species:
21.82
Human Site:
S178
Identified Species:
43.64
UniProt:
Q13467
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13467
NP_003459.2
585
64507
S178
G
P
P
G
A
P
A
S
G
G
E
C
P
A
G
Chimpanzee
Pan troglodytes
XP_526008
585
64475
S178
G
P
P
G
A
P
A
S
G
G
E
C
P
A
G
Rhesus Macaque
Macaca mulatta
XP_001096837
635
68033
G179
P
G
E
Q
P
P
S
G
S
G
H
G
R
P
P
Dog
Lupus familis
XP_545614
589
64543
S178
G
P
A
G
G
P
A
S
G
A
E
C
A
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQD0
585
64119
S178
G
P
P
G
A
P
S
S
G
G
E
C
P
S
G
Rat
Rattus norvegicus
Q8CHL0
585
64093
S178
G
P
P
G
A
P
S
S
G
G
E
C
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9IA06
523
59263
S129
H
S
E
D
G
G
S
S
A
A
L
L
T
S
A
Frog
Xenopus laevis
P58421
559
63500
K165
L
P
P
T
H
P
P
K
V
K
T
P
T
S
D
Zebra Danio
Brachydanio rerio
NP_571209
592
66471
T187
G
T
P
R
H
R
A
T
A
K
S
A
P
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVX3
694
75433
S249
N
P
Q
G
E
K
A
S
G
K
E
C
S
C
S
Honey Bee
Apis mellifera
XP_397259
711
74000
P242
A
P
L
P
A
A
Q
P
R
P
T
R
P
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188449
555
62346
T161
S
N
H
T
N
A
G
T
S
A
P
T
N
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
60.9
96.2
N.A.
96.2
96.4
N.A.
N.A.
45.2
73.3
71.1
N.A.
50.8
48.9
N.A.
61.3
Protein Similarity:
100
99.6
69.1
96.7
N.A.
97.2
97.6
N.A.
N.A.
58.9
81.1
78.5
N.A.
60.9
60.2
N.A.
72.3
P-Site Identity:
100
100
13.3
73.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
20
26.6
N.A.
46.6
20
N.A.
0
P-Site Similarity:
100
100
20
73.3
N.A.
100
100
N.A.
N.A.
20
26.6
33.3
N.A.
46.6
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
42
17
42
0
17
25
0
9
9
25
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
50
0
9
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
17
0
9
0
0
0
0
0
50
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
9
0
50
17
9
9
9
50
42
0
9
0
0
42
% G
% His:
9
0
9
0
17
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
0
9
0
25
0
0
0
0
9
% K
% Leu:
9
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
67
50
9
9
59
9
9
0
9
9
9
50
25
17
% P
% Gln:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
9
0
9
0
0
9
0
0
9
9
0
0
% R
% Ser:
9
9
0
0
0
0
34
59
17
0
9
0
9
42
9
% S
% Thr:
0
9
0
17
0
0
0
17
0
0
17
9
17
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _