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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROCK1
All Species:
26.67
Human Site:
S482
Identified Species:
53.33
UniProt:
Q13464
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13464
NP_005397.1
1354
158175
S482
R
N
L
E
S
T
V
S
Q
I
E
K
E
K
M
Chimpanzee
Pan troglodytes
P61584
1003
117506
K288
T
S
L
Q
E
E
V
K
H
L
K
H
N
L
E
Rhesus Macaque
Macaca mulatta
XP_001091134
1354
158171
S482
R
N
L
E
S
T
V
S
Q
I
E
K
E
K
M
Dog
Lupus familis
XP_537305
2025
232462
S1151
R
N
L
E
S
T
V
S
Q
I
E
K
E
K
M
Cat
Felis silvestris
Mouse
Mus musculus
P70335
1354
158152
S482
R
N
L
E
S
A
V
S
Q
I
E
K
E
K
M
Rat
Rattus norvegicus
Q63644
1369
159608
S482
R
N
L
E
S
A
V
S
Q
I
E
K
E
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505615
1400
161955
S463
R
K
N
Q
T
E
S
S
K
Q
I
Q
Q
L
E
Chicken
Gallus gallus
XP_419151
1358
158654
S484
K
N
L
E
L
T
V
S
Q
I
E
K
E
K
M
Frog
Xenopus laevis
NP_001154860
1372
159002
R485
K
S
I
E
S
T
T
R
Q
L
E
R
E
K
A
Zebra Danio
Brachydanio rerio
NP_777288
1375
159755
R485
K
G
L
E
S
T
L
R
Q
L
E
R
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1B0
1637
186706
S545
R
N
Q
K
Q
K
L
S
R
Q
V
R
D
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198244
1323
154677
M455
L
H
L
Q
N
K
L
M
D
K
E
R
E
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
99.6
65.3
N.A.
96.5
94.8
N.A.
58.2
87.3
64.4
62.4
N.A.
24.3
N.A.
N.A.
47.5
Protein Similarity:
100
74
99.8
66.4
N.A.
98.7
97.4
N.A.
72.5
94.2
80.3
79.4
N.A.
45.8
N.A.
N.A.
66.2
P-Site Identity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
13.3
86.6
46.6
53.3
N.A.
26.6
N.A.
N.A.
20
P-Site Similarity:
100
40
100
100
N.A.
93.3
93.3
N.A.
46.6
93.3
80
80
N.A.
60
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% D
% Glu:
0
0
0
67
9
17
0
0
0
0
75
0
75
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
9
0
0
9
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
50
9
0
0
0
0
% I
% Lys:
25
9
0
9
0
17
0
9
9
9
9
50
0
75
0
% K
% Leu:
9
0
75
0
9
0
25
0
0
25
0
0
0
17
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
50
% M
% Asn:
0
59
9
0
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
25
9
0
0
0
67
17
0
9
9
0
0
% Q
% Arg:
59
0
0
0
0
0
0
17
9
0
0
34
0
0
0
% R
% Ser:
0
17
0
0
59
0
9
67
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
9
50
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
59
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _