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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUSC3
All Species:
40.91
Human Site:
T292
Identified Species:
69.23
UniProt:
Q13454
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13454
NP_006756.2
348
39676
T292
L
V
L
N
A
A
I
T
M
G
M
V
L
L
N
Chimpanzee
Pan troglodytes
XP_001140106
359
41005
T292
L
V
L
N
A
A
I
T
M
G
M
V
L
L
N
Rhesus Macaque
Macaca mulatta
XP_001094069
345
39325
T292
L
V
L
N
A
A
I
T
M
G
M
V
L
L
N
Dog
Lupus familis
XP_849445
348
39645
T292
L
V
L
N
A
A
I
T
M
G
M
V
L
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQY5
335
37951
T280
L
L
F
N
G
G
V
T
L
G
M
V
L
L
C
Rat
Rattus norvegicus
O35777
335
37974
T280
L
L
F
N
G
G
V
T
L
G
M
V
L
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512782
468
52457
T274
L
L
L
N
A
A
I
T
M
G
M
V
L
L
N
Chicken
Gallus gallus
Q5ZJ06
328
36743
T273
L
L
F
N
G
G
V
T
L
G
M
V
L
L
H
Frog
Xenopus laevis
Q63ZR0
329
36900
T274
L
L
F
N
G
A
V
T
L
G
M
V
L
L
H
Zebra Danio
Brachydanio rerio
Q7ZV50
328
37403
T273
L
L
F
N
A
A
V
T
I
G
M
V
L
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609204
330
36992
L277
F
L
N
A
M
I
V
L
G
M
I
L
L
I
E
Honey Bee
Apis mellifera
XP_395605
330
37476
L276
V
L
N
G
A
V
V
L
G
M
I
L
M
I
E
Nematode Worm
Caenorhab. elegans
P34669
331
37670
A260
G
L
L
Y
A
L
I
A
I
G
F
I
C
V
N
Sea Urchin
Strong. purpuratus
XP_782723
331
37476
T276
I
L
L
N
A
A
V
T
C
G
I
I
L
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
98.5
99.7
N.A.
64.9
65.2
N.A.
58.9
68.3
66.6
66.3
N.A.
54
53.7
45.1
60.6
Protein Similarity:
100
96.6
98.5
99.7
N.A.
81.9
81.3
N.A.
62.8
82.7
82.7
81.6
N.A.
72.1
72.4
66
78.7
P-Site Identity:
100
100
100
100
N.A.
53.3
53.3
N.A.
93.3
53.3
60
66.6
N.A.
6.6
6.6
33.3
60
P-Site Similarity:
100
100
100
100
N.A.
73.3
73.3
N.A.
100
80
86.6
93.3
N.A.
40
53.3
60
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
65
58
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% E
% Phe:
8
0
36
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
8
29
22
0
0
15
86
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% H
% Ile:
8
0
0
0
0
8
43
0
15
0
22
15
0
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
72
72
50
0
0
8
0
15
29
0
0
15
86
79
0
% L
% Met:
0
0
0
0
8
0
0
0
36
15
72
0
8
0
0
% M
% Asn:
0
0
15
79
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
79
0
0
0
0
0
0
0
% T
% Val:
8
29
0
0
0
8
58
0
0
0
0
72
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _