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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUSC3 All Species: 31.82
Human Site: S267 Identified Species: 53.85
UniProt: Q13454 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13454 NP_006756.2 348 39676 S267 N P H N G Q V S Y I H G S S Q
Chimpanzee Pan troglodytes XP_001140106 359 41005 S267 N P H N G Q V S Y I H G S S Q
Rhesus Macaque Macaca mulatta XP_001094069 345 39325 S267 N P H N G Q V S Y I H G S S Q
Dog Lupus familis XP_849445 348 39645 S267 N P H N G Q V S Y I H G S S Q
Cat Felis silvestris
Mouse Mus musculus Q9CQY5 335 37951 N255 N P H T G H V N Y I H G S S Q
Rat Rattus norvegicus O35777 335 37974 N255 N P H T G H V N Y I H G S S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512782 468 52457 S249 N P Q N G Q V S Y I H G S S Q
Chicken Gallus gallus Q5ZJ06 328 36743 N248 N P H T G Q V N Y I H G S S Q
Frog Xenopus laevis Q63ZR0 329 36900 N249 N P H T N Q V N Y I H G S S Q
Zebra Danio Brachydanio rerio Q7ZV50 328 37403 S248 N P N T G Q V S Y I H G S S Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609204 330 36992 Y252 S Q N G G V A Y I H G S S Q G
Honey Bee Apis mellifera XP_395605 330 37476 Y251 S A S G N V A Y I H A S S Q G
Nematode Worm Caenorhab. elegans P34669 331 37670 S235 N P N T K E P S F I H G S T Q
Sea Urchin Strong. purpuratus XP_782723 331 37476 S251 N P Q N G Q V S Y I H G S S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 98.5 99.7 N.A. 64.9 65.2 N.A. 58.9 68.3 66.6 66.3 N.A. 54 53.7 45.1 60.6
Protein Similarity: 100 96.6 98.5 99.7 N.A. 81.9 81.3 N.A. 62.8 82.7 82.7 81.6 N.A. 72.1 72.4 66 78.7
P-Site Identity: 100 100 100 100 N.A. 80 80 N.A. 93.3 86.6 80 86.6 N.A. 13.3 6.6 53.3 93.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 93.3 93.3 86.6 93.3 N.A. 26.6 13.3 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 15 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 15 79 0 0 0 0 0 8 86 0 0 15 % G
% His: 0 0 58 0 0 15 0 0 0 15 86 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 86 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 86 0 22 43 15 0 0 29 0 0 0 0 0 0 0 % N
% Pro: 0 86 0 0 0 0 8 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 15 0 0 65 0 0 0 0 0 0 0 15 86 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 15 0 8 0 0 0 0 58 0 0 0 15 100 79 0 % S
% Thr: 0 0 0 43 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 15 79 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 15 79 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _