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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC119 All Species: 7.88
Human Site: S35 Identified Species: 14.44
UniProt: Q13432 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13432 NP_005139.1 240 26962 S35 I P Q P P A E S E S G S E S E
Chimpanzee Pan troglodytes XP_001145903 240 26909 S35 I P Q P P A E S E S G S E S E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548289 242 27285 A35 K P E P Q L Q A E S E S G S E
Cat Felis silvestris
Mouse Mus musculus Q9Z2R6 240 26992 A35 T R E P G A E A E S G S E S E
Rat Rattus norvegicus Q62885 240 27030 A35 T R E P G A E A E S G S E S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507167 238 27498 W31 N G P V G S D W G C Q S P A R
Chicken Gallus gallus XP_001234937 206 23644 A24 E E E L G R K A L I G P D D V
Frog Xenopus laevis Q66JA9 242 27986 G36 L K A R R V Q G K E S G T S D
Zebra Danio Brachydanio rerio Q90Z08 243 27991 R46 S R R N Q V D R R P V T E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYQ2 265 28394 G44 E A N G G S G G S S G A A A A
Honey Bee Apis mellifera XP_396881 222 25437 T31 N T D N G N I T E N I I T P E
Nematode Worm Caenorhab. elegans Q10658 219 25245 T34 V T E Q A I T T E A E L L A K
Sea Urchin Strong. purpuratus XP_787370 240 27263 N38 K E K K A H S N S E E T V T E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 92.5 N.A. 91.6 92 N.A. 63.3 70.8 55.7 53.9 N.A. 51.7 55.4 49.5 55
Protein Similarity: 100 98.7 N.A. 94.2 N.A. 93.7 93.7 N.A. 71.2 77.9 69 67.4 N.A. 64.1 69.1 65.8 69.1
P-Site Identity: 100 100 N.A. 46.6 N.A. 66.6 66.6 N.A. 6.6 6.6 6.6 13.3 N.A. 13.3 13.3 6.6 6.6
P-Site Similarity: 100 100 N.A. 66.6 N.A. 80 80 N.A. 26.6 33.3 33.3 33.3 N.A. 33.3 26.6 46.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 16 31 0 31 0 8 0 8 8 24 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 16 0 0 0 0 0 8 8 8 % D
% Glu: 16 16 39 0 0 0 31 0 54 16 24 0 39 8 62 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 47 0 8 16 8 0 47 8 8 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 8 8 0 0 8 8 8 0 0 0 % I
% Lys: 16 8 8 8 0 0 8 0 8 0 0 0 0 0 8 % K
% Leu: 8 0 0 8 0 8 0 0 8 0 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 8 16 0 8 0 8 0 8 0 0 0 0 0 % N
% Pro: 0 24 8 39 16 0 0 0 0 8 0 8 8 8 0 % P
% Gln: 0 0 16 8 16 0 16 0 0 0 8 0 0 0 0 % Q
% Arg: 0 24 8 8 8 8 0 8 8 0 0 0 0 0 8 % R
% Ser: 8 0 0 0 0 16 8 16 16 47 8 47 0 47 0 % S
% Thr: 16 16 0 0 0 0 8 16 0 0 0 16 16 8 0 % T
% Val: 8 0 0 8 0 16 0 0 0 0 8 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _