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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC119 All Species: 43.33
Human Site: S216 Identified Species: 79.44
UniProt: Q13432 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13432 NP_005139.1 240 26962 S216 R H P Y E T Q S D S F Y F V D
Chimpanzee Pan troglodytes XP_001145903 240 26909 S216 R H P Y E T Q S D S F Y F V D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548289 242 27285 S218 R H P Y E T Q S D S F Y F V D
Cat Felis silvestris
Mouse Mus musculus Q9Z2R6 240 26992 S216 R H P Y E T Q S D S F Y F V D
Rat Rattus norvegicus Q62885 240 27030 S216 R H P Y E T Q S D S F Y F V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507167 238 27498 S214 R H P Y E T Q S D S F Y F V D
Chicken Gallus gallus XP_001234937 206 23644 D183 H P Y E T Q S D S F Y F V D N
Frog Xenopus laevis Q66JA9 242 27986 S218 E N P Y E T R S D S F Y F V D
Zebra Danio Brachydanio rerio Q90Z08 243 27991 S219 E H P Y E T R S D S F Y F V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYQ2 265 28394 S239 S S P F E T R S D S F Y F V G
Honey Bee Apis mellifera XP_396881 222 25437 S193 A N P F E T R S D S F Y F V D
Nematode Worm Caenorhab. elegans Q10658 219 25245 R196 I N N P N E T R S D S F Y F V
Sea Urchin Strong. purpuratus XP_787370 240 27263 S213 D N P F E T K S D S F Y F V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 92.5 N.A. 91.6 92 N.A. 63.3 70.8 55.7 53.9 N.A. 51.7 55.4 49.5 55
Protein Similarity: 100 98.7 N.A. 94.2 N.A. 93.7 93.7 N.A. 71.2 77.9 69 67.4 N.A. 64.1 69.1 65.8 69.1
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 0 80 86.6 N.A. 66.6 73.3 0 73.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 20 93.3 93.3 N.A. 80 93.3 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 8 85 8 0 0 0 8 77 % D
% Glu: 16 0 0 8 85 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 24 0 0 0 0 0 8 85 16 85 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 8 54 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 31 8 0 8 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 8 85 8 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 47 0 0 0 0 0 0 0 0 % Q
% Arg: 47 0 0 0 0 0 31 8 0 0 0 0 0 0 0 % R
% Ser: 8 8 0 0 0 0 8 85 16 85 8 0 0 0 0 % S
% Thr: 0 0 0 0 8 85 8 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 85 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 62 0 0 0 0 0 0 8 85 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _