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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC119 All Species: 23.03
Human Site: S111 Identified Species: 42.22
UniProt: Q13432 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13432 NP_005139.1 240 26962 S111 E I K K P P V S E R L P I N R
Chimpanzee Pan troglodytes XP_001145903 240 26909 S111 E I K K P P V S E R L P I N R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548289 242 27285 S113 E I K K P P A S E R L P I N R
Cat Felis silvestris
Mouse Mus musculus Q9Z2R6 240 26992 S111 E I K K P P V S E R L P I N R
Rat Rattus norvegicus Q62885 240 27030 S111 E I K K P P V S E R L P I N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507167 238 27498 S109 E I T K P P A S E R D R G D K
Chicken Gallus gallus XP_001234937 206 23644 K84 S E R E H N D K K D V D P N A
Frog Xenopus laevis Q66JA9 242 27986 E112 E I S K P C S E Q E E E E E E
Zebra Danio Brachydanio rerio Q90Z08 243 27991 C112 E I A K P P H C D L D E E D D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9XYQ2 265 28394 E119 E I A K P P S E Q Y P E G L S
Honey Bee Apis mellifera XP_396881 222 25437 E93 T D V E S E I E E S G C E D A
Nematode Worm Caenorhab. elegans Q10658 219 25245 E95 E I A K P E N E T E E N L Q A
Sea Urchin Strong. purpuratus XP_787370 240 27263 S105 E I A K P P P S E N D D D V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 92.5 N.A. 91.6 92 N.A. 63.3 70.8 55.7 53.9 N.A. 51.7 55.4 49.5 55
Protein Similarity: 100 98.7 N.A. 94.2 N.A. 93.7 93.7 N.A. 71.2 77.9 69 67.4 N.A. 64.1 69.1 65.8 69.1
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 53.3 6.6 26.6 33.3 N.A. 33.3 6.6 26.6 46.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 66.6 33.3 33.3 46.6 N.A. 40 26.6 33.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 31 0 0 0 16 0 0 0 0 0 0 0 24 % A
% Cys: 0 0 0 0 0 8 0 8 0 0 0 8 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 0 8 8 24 16 8 24 8 % D
% Glu: 85 8 0 16 0 16 0 31 62 16 16 24 24 8 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 16 0 0 % G
% His: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 85 0 0 0 0 8 0 0 0 0 0 39 0 0 % I
% Lys: 0 0 39 85 0 0 0 8 8 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 0 0 8 39 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 8 0 0 8 0 8 0 47 0 % N
% Pro: 0 0 0 0 85 70 8 0 0 0 8 39 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 16 0 0 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 47 0 8 0 0 39 % R
% Ser: 8 0 8 0 8 0 16 54 0 8 0 0 0 0 8 % S
% Thr: 8 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 31 0 0 0 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _