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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCOF1
All Species:
6.67
Human Site:
S1473
Identified Species:
16.3
UniProt:
Q13428
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13428
NP_000347.2
1488
152104
S1473
T
K
D
S
E
S
P
S
Q
K
K
K
K
K
K
Chimpanzee
Pan troglodytes
XP_527074
1411
144549
Q1397
K
D
S
E
S
P
S
Q
K
K
K
K
K
K
K
Rhesus Macaque
Macaca mulatta
NP_001035041
1485
152021
S1470
T
K
D
S
E
S
P
S
Q
K
K
K
K
K
K
Dog
Lupus familis
XP_851848
704
74723
G690
K
R
G
S
Y
R
G
G
S
I
S
V
Q
V
N
Cat
Felis silvestris
Mouse
Mus musculus
O08784
1320
134983
Q1306
K
D
S
A
S
P
I
Q
K
K
K
K
K
K
K
Rat
Rattus norvegicus
P41777
704
73545
G690
K
R
G
S
Y
R
G
G
S
I
S
V
Q
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510162
1294
129807
R1280
I
K
V
T
G
G
G
R
L
G
E
S
S
D
E
Chicken
Gallus gallus
NP_001012803
974
101012
K960
G
S
A
E
V
H
K
K
K
K
K
K
K
K
T
Frog
Xenopus laevis
NP_001089103
1476
154336
S1461
P
G
S
A
T
G
I
S
P
K
P
K
K
K
K
Zebra Danio
Brachydanio rerio
XP_689627
1001
102013
G987
K
R
G
S
Y
R
G
G
A
I
S
T
T
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.9
85.8
23.8
N.A.
50.2
24.9
N.A.
23.7
29.8
20.8
29.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.5
88.7
33.4
N.A.
60.4
33.8
N.A.
37.5
41.5
36.9
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
40
100
6.6
N.A.
40
6.6
N.A.
6.6
33.3
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
20
N.A.
53.3
20
N.A.
26.6
40
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
20
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
20
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
20
20
0
0
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
30
0
10
20
40
30
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
20
0
0
30
0
0
0
0
0
% I
% Lys:
50
30
0
0
0
0
10
10
30
60
50
60
60
60
50
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% N
% Pro:
10
0
0
0
0
20
20
0
10
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
20
20
0
0
0
20
0
0
% Q
% Arg:
0
30
0
0
0
30
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
10
30
50
20
20
10
30
20
0
30
10
10
0
0
% S
% Thr:
20
0
0
10
10
0
0
0
0
0
0
10
10
0
10
% T
% Val:
0
0
10
0
10
0
0
0
0
0
0
20
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _