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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC4
All Species:
11.82
Human Site:
S299
Identified Species:
28.89
UniProt:
Q13426
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13426
NP_003392.1
336
38287
S299
Q
L
Q
E
K
E
N
S
R
P
D
S
S
L
P
Chimpanzee
Pan troglodytes
XP_001148110
336
38223
S299
Q
L
Q
E
K
E
N
S
K
P
D
S
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001111757
336
38393
S299
Q
F
Q
E
K
E
N
S
R
P
D
S
S
L
P
Dog
Lupus familis
XP_849518
335
38080
S298
Q
P
Q
E
K
K
K
S
R
L
D
P
P
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q924T3
326
37042
K290
Q
E
L
P
L
Q
E
K
E
R
L
A
S
S
L
Rat
Rattus norvegicus
NP_001007000
323
36459
P283
K
M
A
P
Q
E
L
P
L
Q
E
K
E
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424905
234
26756
L198
K
K
M
K
I
R
N
L
Q
K
L
L
N
E
A
Frog
Xenopus laevis
NP_001085360
362
40705
Q325
K
T
S
N
E
E
T
Q
R
C
N
P
A
P
A
Zebra Danio
Brachydanio rerio
NP_957080
357
40801
R320
L
E
Q
Q
H
R
S
R
E
K
P
V
E
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181652
239
26963
I203
D
R
P
L
A
A
S
I
H
G
D
S
G
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.6
79.1
N.A.
73.8
70.5
N.A.
N.A.
42.8
44.2
38
N.A.
N.A.
N.A.
N.A.
20.2
Protein Similarity:
100
99.4
97
85.4
N.A.
80.6
77.9
N.A.
N.A.
51.7
59.3
55.4
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
93.3
93.3
60
N.A.
13.3
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
66.6
N.A.
26.6
33.3
N.A.
N.A.
33.3
40
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
0
0
0
0
0
10
10
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% D
% Glu:
0
20
0
40
10
50
10
0
20
0
10
0
20
20
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
30
10
0
10
40
10
10
10
10
20
0
10
0
0
0
% K
% Leu:
10
20
10
10
10
0
10
10
10
10
20
10
0
40
20
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
40
0
0
0
10
0
10
0
0
% N
% Pro:
0
10
10
20
0
0
0
10
0
30
10
20
10
10
40
% P
% Gln:
50
0
50
10
10
10
0
10
10
10
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
20
0
10
40
10
0
0
0
10
0
% R
% Ser:
0
0
10
0
0
0
20
40
0
0
0
40
40
20
0
% S
% Thr:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _