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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILK All Species: 37.27
Human Site: S396 Identified Species: 68.33
UniProt: Q13418 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13418 NP_001014794.1 452 51419 S396 E V P F A D L S N M E I G M K
Chimpanzee Pan troglodytes XP_001164277 401 45629 P368 T I P P G I S P H V C K L M K
Rhesus Macaque Macaca mulatta XP_001108844 482 54677 S426 E V P F A D L S N M E I G M K
Dog Lupus familis XP_534040 452 51371 S396 E V P F A D L S N M E I G M K
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q99J82 452 51355 S396 E V P F A D L S N M E I G M K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09324 541 60774 M474 G R V P Y P G M V N R E V L E
Frog Xenopus laevis NP_001086805 452 51540 S396 E V P F A D L S N M E I G M K
Zebra Danio Brachydanio rerio NP_956865 452 51045 S396 E V P F A D L S N M E I G M K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525001 448 50724 S393 E V P F A E W S P M E C G M K
Honey Bee Apis mellifera XP_396799 449 50561 S394 E V P F A D L S P M E C G M K
Nematode Worm Caenorhab. elegans NP_497139 466 52241 P411 E V P F S D L P P M E C G M K
Sea Urchin Strong. purpuratus XP_786444 448 50461 S392 E V P F A G M S S M E V G M K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001152374 534 58727 T459 K I P Y N T M T P L Q A A V G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 93.7 99.7 N.A. N.A. 99.5 N.A. N.A. 23.4 88.9 86.7 N.A. 60.1 61.5 56.4 59.5
Protein Similarity: 100 88.7 93.7 99.7 N.A. N.A. 99.7 N.A. N.A. 39.9 94.6 93.3 N.A. 75.4 77.2 75.5 79.4
P-Site Identity: 100 20 100 100 N.A. N.A. 100 N.A. N.A. 0 100 100 N.A. 73.3 86.6 73.3 73.3
P-Site Similarity: 100 40 100 100 N.A. N.A. 100 N.A. N.A. 13.3 100 100 N.A. 80 86.6 80 93.3
Percent
Protein Identity: N.A. 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 44.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 60 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 70 0 0 0 0 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 24 0 0 0 % C
% Asp: 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 % D
% Glu: 77 0 0 0 0 8 0 0 0 0 77 8 0 0 8 % E
% Phe: 0 0 0 77 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 8 8 8 0 0 0 0 0 77 0 8 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 16 0 0 0 8 0 0 0 0 0 47 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 85 % K
% Leu: 0 0 0 0 0 0 62 0 0 8 0 0 8 8 0 % L
% Met: 0 0 0 0 0 0 16 8 0 77 0 0 0 85 0 % M
% Asn: 0 0 0 0 8 0 0 0 47 8 0 0 0 0 0 % N
% Pro: 0 0 93 16 0 8 0 16 31 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 8 0 8 70 8 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % T
% Val: 0 77 8 0 0 0 0 0 8 8 0 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _