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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILK All Species: 21.52
Human Site: S259 Identified Species: 39.44
UniProt: Q13418 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13418 NP_001014794.1 452 51419 S259 P V L G A C Q S P P A P H P T
Chimpanzee Pan troglodytes XP_001164277 401 45629 N235 N V L H E G T N F V V D Q S Q
Rhesus Macaque Macaca mulatta XP_001108844 482 54677 S289 P V L G A C Q S P P A P H P T
Dog Lupus familis XP_534040 452 51371 S259 P V L G A C Q S P P A P H P T
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q99J82 452 51355 A259 P V L G A C Q A P P A P H P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09324 541 60774 V336 K L V P L Y A V V S E E P I Y
Frog Xenopus laevis NP_001086805 452 51540 S259 P V L G A C Q S P P A P H P V
Zebra Danio Brachydanio rerio NP_956865 452 51045 S259 P V L G A C Q S P P A P H P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525001 448 50724 S258 P I I G A C N S P P N L V T I
Honey Bee Apis mellifera XP_396799 449 50561 Q258 P V L G C V N Q P P K L A T V
Nematode Worm Caenorhab. elegans NP_497139 466 52241 A274 I C A V L A A A N Q P P N L V
Sea Urchin Strong. purpuratus XP_786444 448 50461 Q257 P V L G C V N Q P P N L V V L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001152374 534 58727 S323 N I V R F I G S C T K P P Q F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 93.7 99.7 N.A. N.A. 99.5 N.A. N.A. 23.4 88.9 86.7 N.A. 60.1 61.5 56.4 59.5
Protein Similarity: 100 88.7 93.7 99.7 N.A. N.A. 99.7 N.A. N.A. 39.9 94.6 93.3 N.A. 75.4 77.2 75.5 79.4
P-Site Identity: 100 13.3 100 100 N.A. N.A. 93.3 N.A. N.A. 0 93.3 93.3 N.A. 46.6 40 6.6 40
P-Site Similarity: 100 20 100 100 N.A. N.A. 100 N.A. N.A. 13.3 93.3 93.3 N.A. 60 40 20 40
Percent
Protein Identity: N.A. 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 44.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 54 8 16 16 0 0 47 0 8 0 0 % A
% Cys: 0 8 0 0 16 54 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 0 0 0 70 0 8 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 47 0 0 % H
% Ile: 8 16 8 0 0 8 0 0 0 0 0 0 0 8 16 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % K
% Leu: 0 8 70 0 16 0 0 0 0 0 0 24 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 0 0 0 0 24 8 8 0 16 0 8 0 0 % N
% Pro: 70 0 0 8 0 0 0 0 70 70 8 62 16 47 0 % P
% Gln: 0 0 0 0 0 0 47 16 0 8 0 0 8 8 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 54 0 8 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 8 0 0 8 0 0 0 16 31 % T
% Val: 0 70 16 8 0 16 0 8 8 8 8 0 16 8 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _