Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ILK All Species: 34.55
Human Site: S246 Identified Species: 63.33
UniProt: Q13418 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13418 NP_001014794.1 452 51419 S246 C P R L R I F S H P N V L P V
Chimpanzee Pan troglodytes XP_001164277 401 45629 P222 T L I T H W M P Y G S L Y N V
Rhesus Macaque Macaca mulatta XP_001108844 482 54677 S276 C P R L R I F S H P N V L P V
Dog Lupus familis XP_534040 452 51371 S246 C P R L R I F S H P N V L P V
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q99J82 452 51355 S246 C P R L R I F S H P N V L P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09324 541 60774 K323 L Q E A Q I M K K L R H D K L
Frog Xenopus laevis NP_001086805 452 51540 S246 Y P K L R I F S H P N V L P V
Zebra Danio Brachydanio rerio NP_956865 452 51045 S246 Y P K L R I F S H P N V L P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525001 448 50724 S245 F P K L R I F S H P N I L P I
Honey Bee Apis mellifera XP_396799 449 50561 S245 F P K L R I F S H P N V L P V
Nematode Worm Caenorhab. elegans NP_497139 466 52241 I261 T E F P A L R I F A H P N I C
Sea Urchin Strong. purpuratus XP_786444 448 50461 S244 F P R L R I F S H P N I H P V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001152374 534 58727 R310 K Q E I N M L R E V D H P N I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.7 93.7 99.7 N.A. N.A. 99.5 N.A. N.A. 23.4 88.9 86.7 N.A. 60.1 61.5 56.4 59.5
Protein Similarity: 100 88.7 93.7 99.7 N.A. N.A. 99.7 N.A. N.A. 39.9 94.6 93.3 N.A. 75.4 77.2 75.5 79.4
P-Site Identity: 100 6.6 100 100 N.A. N.A. 100 N.A. N.A. 6.6 86.6 86.6 N.A. 73.3 86.6 0 80
P-Site Similarity: 100 26.6 100 100 N.A. N.A. 100 N.A. N.A. 20 93.3 93.3 N.A. 93.3 93.3 13.3 86.6
Percent
Protein Identity: N.A. 24.5 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 44.3 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 0 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 31 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % D
% Glu: 0 8 16 0 0 0 0 0 8 0 0 0 0 0 0 % E
% Phe: 24 0 8 0 0 0 70 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 70 0 8 16 8 0 0 % H
% Ile: 0 0 8 8 0 77 0 8 0 0 0 16 0 8 16 % I
% Lys: 8 0 31 0 0 0 0 8 8 0 0 0 0 8 0 % K
% Leu: 8 8 0 70 0 8 8 0 0 8 0 8 62 0 8 % L
% Met: 0 0 0 0 0 8 16 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 70 0 8 16 0 % N
% Pro: 0 70 0 8 0 0 0 8 0 70 0 8 8 70 0 % P
% Gln: 0 16 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 39 0 70 0 8 8 0 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 70 0 0 8 0 0 0 0 % S
% Thr: 16 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 54 0 0 70 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _