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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC2L All Species: 34.85
Human Site: S475 Identified Species: 54.76
UniProt: Q13416 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13416 NP_006181.1 577 65972 S475 Q S G S L P L S S L T H V L R
Chimpanzee Pan troglodytes XP_516023 646 73228 S544 Q S G S L P L S S L T H V L R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536028 577 66097 S475 Q S G S L P L S S L I H V L R
Cat Felis silvestris
Mouse Mus musculus Q60862 576 65875 S474 Q S G S L P L S S L I H V L R
Rat Rattus norvegicus Q75PQ8 576 65831 S473 Q S G S L P L S S L I H V L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520674 406 46742 H307 L A L S S L T H V I R S L T P
Chicken Gallus gallus NP_001006517 569 64216 S467 Q S G S L A L S S L T H V L R
Frog Xenopus laevis Q91628 558 62908 S456 R S G A L A L S S L T H V L R
Zebra Danio Brachydanio rerio NP_001070772 553 62538 S452 Q T G A L A L S S L T H V L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24168 618 68977 S517 N S G E L A L S S M R S V F S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21037 430 49301 V331 H T M S S L D V F W K S L A V
Sea Urchin Strong. purpuratus XP_789987 337 38784 S238 S G M L A L S S L T H V L R S
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105071 377 42494 Q278 L A S G G H A Q T T K T A L V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38899 363 40793 T264 A Q G S T A Q T A K T A A I V
Baker's Yeast Sacchar. cerevisiae P32833 620 71220 A507 K S D T S S G A E G A K Y V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 N.A. 91.6 N.A. 78.8 78.6 N.A. 55.9 66.7 61 55.6 N.A. 34.9 N.A. 24 35.1
Protein Similarity: 100 87.1 N.A. 95.6 N.A. 88.3 87.8 N.A. 64.8 81.2 77.9 72.7 N.A. 54.3 N.A. 42.9 46.9
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 93.3 80 80 N.A. 46.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 26.6 93.3 93.3 93.3 N.A. 53.3 N.A. 20 13.3
Percent
Protein Identity: N.A. 24.9 N.A. 24.9 20.6 N.A.
Protein Similarity: N.A. 38.6 N.A. 39.5 43 N.A.
P-Site Identity: N.A. 6.6 N.A. 20 6.6 N.A.
P-Site Similarity: N.A. 20 N.A. 40 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 0 14 7 34 7 7 7 0 7 7 14 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % F
% Gly: 0 7 67 7 7 0 7 0 0 7 0 0 0 0 0 % G
% His: 7 0 0 0 0 7 0 7 0 0 7 54 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 20 0 0 7 0 % I
% Lys: 7 0 0 0 0 0 0 0 0 7 14 7 0 0 0 % K
% Leu: 14 0 7 7 60 20 60 0 7 54 0 0 20 60 7 % L
% Met: 0 0 14 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 7 % P
% Gln: 47 7 0 0 0 0 7 7 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 14 0 0 7 54 % R
% Ser: 7 60 7 60 20 7 7 67 60 0 0 20 0 0 14 % S
% Thr: 0 14 0 7 7 0 7 7 7 14 40 7 0 7 0 % T
% Val: 0 0 0 0 0 0 0 7 7 0 0 7 60 7 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _