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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC2L
All Species:
18.48
Human Site:
S277
Identified Species:
29.05
UniProt:
Q13416
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13416
NP_006181.1
577
65972
S277
Q
T
L
R
N
L
L
S
K
V
S
P
S
F
S
Chimpanzee
Pan troglodytes
XP_516023
646
73228
S346
Q
T
L
R
N
L
L
S
K
V
S
P
S
F
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536028
577
66097
S277
Q
T
L
R
N
L
L
S
K
V
S
P
S
F
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60862
576
65875
R276
K
T
L
H
N
L
L
R
K
F
V
P
S
F
S
Rat
Rattus norvegicus
Q75PQ8
576
65831
S275
K
T
L
R
N
L
L
S
K
F
V
P
S
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520674
406
46742
K116
P
T
F
S
A
E
L
K
Q
L
N
Q
Q
H
E
Chicken
Gallus gallus
NP_001006517
569
64216
Q269
Q
T
L
H
D
L
L
Q
K
S
P
L
A
Y
A
Frog
Xenopus laevis
Q91628
558
62908
D258
E
T
L
R
K
L
L
D
Q
T
P
S
A
F
A
Zebra Danio
Brachydanio rerio
NP_001070772
553
62538
G254
E
T
L
L
G
L
L
G
K
N
T
P
R
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24168
618
68977
S317
D
R
V
F
S
L
L
S
E
I
K
T
S
A
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21037
430
49301
L140
N
T
E
F
E
K
R
L
E
H
L
A
D
N
D
Sea Urchin
Strong. purpuratus
XP_789987
337
38784
E47
A
P
N
S
Y
T
K
E
M
R
E
L
F
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105071
377
42494
R87
R
S
Y
K
D
Q
Y
R
N
W
L
F
E
L
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38899
363
40793
S73
S
D
Y
K
T
M
Y
S
K
W
V
F
E
L
R
Baker's Yeast
Sacchar. cerevisiae
P32833
620
71220
T270
M
S
M
A
P
D
V
T
R
E
E
F
S
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.2
N.A.
91.6
N.A.
78.8
78.6
N.A.
55.9
66.7
61
55.6
N.A.
34.9
N.A.
24
35.1
Protein Similarity:
100
87.1
N.A.
95.6
N.A.
88.3
87.8
N.A.
64.8
81.2
77.9
72.7
N.A.
54.3
N.A.
42.9
46.9
P-Site Identity:
100
100
N.A.
100
N.A.
66.6
80
N.A.
13.3
40
40
46.6
N.A.
26.6
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
73.3
86.6
N.A.
33.3
66.6
66.6
66.6
N.A.
53.3
N.A.
13.3
0
Percent
Protein Identity:
N.A.
24.9
N.A.
24.9
20.6
N.A.
Protein Similarity:
N.A.
38.6
N.A.
39.5
43
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
0
0
0
0
0
0
7
14
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
14
7
0
7
0
0
0
0
7
0
7
% D
% Glu:
14
0
7
0
7
7
0
7
14
7
14
0
14
7
20
% E
% Phe:
0
0
7
14
0
0
0
0
0
14
0
20
7
47
0
% F
% Gly:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
14
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
14
0
0
14
7
7
7
7
54
0
7
0
0
0
0
% K
% Leu:
0
0
54
7
0
60
67
7
0
7
14
14
0
20
0
% L
% Met:
7
0
7
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
7
0
7
0
34
0
0
0
7
7
7
0
0
7
0
% N
% Pro:
7
7
0
0
7
0
0
0
0
0
14
40
0
0
0
% P
% Gln:
27
0
0
0
0
7
0
7
14
0
0
7
7
0
0
% Q
% Arg:
7
7
0
34
0
0
7
14
7
7
0
0
7
0
14
% R
% Ser:
7
14
0
14
7
0
0
40
0
7
20
7
47
0
34
% S
% Thr:
0
67
0
0
7
7
0
7
0
7
7
7
0
0
0
% T
% Val:
0
0
7
0
0
0
7
0
0
20
20
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% W
% Tyr:
0
0
14
0
7
0
14
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _