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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCL All Species: 14.24
Human Site: S39 Identified Species: 31.33
UniProt: Q13371 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13371 NP_005379.3 301 34282 S39 R G R C A P A S S S V P A E A
Chimpanzee Pan troglodytes XP_528422 301 34291 S39 R G R G A P A S S S V P A E A
Rhesus Macaque Macaca mulatta XP_001086958 301 34204 S39 P G R G A P A S S S V P A E A
Dog Lupus familis XP_852231 301 34185 G39 G G R G A L A G T S M P A D A
Cat Felis silvestris
Mouse Mus musculus Q9DBX2 301 34388 I39 R G R G A P A I S S T P A E A
Rat Rattus norvegicus Q63737 301 34255 S39 R G R G A P A S S S T P A E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512023 299 33951 S39 K G A T L D E S V P G E A E L
Chicken Gallus gallus XP_001234493 300 34411 P39 K E G E S S I P D S V G E V E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUR7 276 30957 S39 N K G A S G K S R C S G L T I
Honey Bee Apis mellifera XP_393706 284 32413 K39 D K E T E D E K Y P Q I I T D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799253 293 33509 K39 S S G D E Q N K D C A A S P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 98 93 N.A. 92 92.3 N.A. 80 75.4 N.A. N.A. N.A. 43.8 46.5 N.A. 48.5
Protein Similarity: 100 99.6 99.3 97.6 N.A. 96 96.6 N.A. 90 88.3 N.A. N.A. N.A. 61.1 66.7 N.A. 67.7
P-Site Identity: 100 93.3 86.6 53.3 N.A. 80 86.6 N.A. 26.6 13.3 N.A. N.A. N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 93.3 86.6 73.3 N.A. 80 86.6 N.A. 33.3 26.6 N.A. N.A. N.A. 13.3 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 55 0 55 0 0 0 10 10 64 0 55 % A
% Cys: 0 0 0 10 0 0 0 0 0 19 0 0 0 0 0 % C
% Asp: 10 0 0 10 0 19 0 0 19 0 0 0 0 10 10 % D
% Glu: 0 10 10 10 19 0 19 0 0 0 0 10 10 55 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 64 28 46 0 10 0 10 0 0 10 19 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 0 0 10 10 0 10 % I
% Lys: 19 19 0 0 0 0 10 19 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 10 0 0 0 0 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 46 0 10 0 19 0 55 0 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 37 0 55 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 10 0 0 19 10 0 55 46 64 10 0 10 0 0 % S
% Thr: 0 0 0 19 0 0 0 0 10 0 19 0 0 19 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 37 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _