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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRHR2
All Species:
33.33
Human Site:
S396
Identified Species:
81.48
UniProt:
Q13324
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13324
NP_001874.2
411
47688
S396
R
A
M
S
I
P
T
S
P
T
R
I
S
F
H
Chimpanzee
Pan troglodytes
XP_001160981
495
56526
S480
R
A
M
S
I
P
T
S
P
T
R
I
S
F
H
Rhesus Macaque
Macaca mulatta
Q76LL8
415
47765
S400
R
A
M
S
I
P
T
S
P
T
R
V
S
F
H
Dog
Lupus familis
XP_539501
411
47717
S396
R
A
M
S
I
P
T
S
P
T
R
I
S
F
H
Cat
Felis silvestris
Mouse
Mus musculus
Q60748
431
49905
S416
R
A
M
S
I
P
T
S
P
T
R
I
S
F
H
Rat
Rattus norvegicus
P47866
411
47688
S396
R
A
M
S
I
P
T
S
P
T
R
I
S
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90812
420
48581
S405
R
A
M
S
I
P
T
S
P
T
R
V
S
F
H
Frog
Xenopus laevis
O42603
413
48440
S398
R
A
M
S
I
P
T
S
P
T
R
I
S
F
H
Zebra Danio
Brachydanio rerio
Q68EK2
470
54084
T430
A
L
R
S
A
S
Y
T
A
S
S
I
T
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W4Y2
669
74467
G535
K
R
A
S
M
Y
S
G
A
Y
N
T
A
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
69.1
96.1
N.A.
83.9
93.9
N.A.
N.A.
70.2
80.8
26.8
N.A.
25.8
N.A.
N.A.
N.A.
Protein Similarity:
100
80.1
81.9
98.5
N.A.
89.5
97
N.A.
N.A.
81.9
88.6
45.9
N.A.
37.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
100
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
33.3
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
80
10
0
10
0
0
0
20
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
80
% H
% Ile:
0
0
0
0
80
0
0
0
0
0
0
70
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
80
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
80
0
0
80
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
80
10
10
0
0
0
0
0
0
0
80
0
0
0
0
% R
% Ser:
0
0
0
100
0
10
10
80
0
10
10
0
80
0
0
% S
% Thr:
0
0
0
0
0
0
80
10
0
80
0
10
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _