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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD2L1
All Species:
37.01
Human Site:
Y199
Identified Species:
54.29
UniProt:
Q13257
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13257
NP_002349.1
205
23510
Y199
K
V
N
S
M
V
A
Y
K
I
P
V
N
D
_
Chimpanzee
Pan troglodytes
XP_517581
196
22483
Rhesus Macaque
Macaca mulatta
XP_001084989
205
23614
Y199
K
V
N
S
M
V
A
Y
K
I
P
V
N
D
_
Dog
Lupus familis
XP_533278
205
23552
Y199
K
V
N
S
M
V
A
Y
K
I
P
T
N
D
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B5
205
23580
Y199
K
V
N
S
M
V
A
Y
K
T
P
V
N
D
_
Rat
Rattus norvegicus
NP_001100064
205
23520
Y199
K
V
N
S
M
V
A
Y
K
T
P
V
S
D
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513397
205
23385
Y199
K
V
N
S
M
V
A
Y
K
I
P
V
S
D
_
Chicken
Gallus gallus
XP_420629
206
23693
Y200
K
V
N
S
M
V
A
Y
K
K
D
S
F
P
_
Frog
Xenopus laevis
NP_001080741
203
23361
Zebra Danio
Brachydanio rerio
NP_001017739
202
23158
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023563
203
23510
Sea Urchin
Strong. purpuratus
XP_001178696
206
23671
Y200
K
V
D
A
M
V
S
Y
K
L
M
D
G
I
_
Poplar Tree
Populus trichocarpa
XP_002311730
207
23536
Y199
K
V
D
T
L
V
S
Y
K
N
D
E
W
D
E
Maize
Zea mays
Q9XFH3
208
23486
Y199
K
V
D
T
L
V
S
Y
K
K
D
E
W
D
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LU93
209
23713
Y200
K
V
D
T
L
V
S
Y
K
N
D
E
W
D
E
Baker's Yeast
Sacchar. cerevisiae
P40958
196
22266
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.6
97.5
97.5
N.A.
94.1
94.1
N.A.
93.6
86.8
80.4
74.1
N.A.
N.A.
N.A.
50.2
65
Protein Similarity:
100
95.6
97.5
98.5
N.A.
96
97
N.A.
97.5
92.2
89.2
86.8
N.A.
N.A.
N.A.
72.1
77.6
P-Site Identity:
100
0
100
92.8
N.A.
92.8
85.7
N.A.
92.8
64.2
0
0
N.A.
N.A.
N.A.
0
42.8
P-Site Similarity:
100
0
100
92.8
N.A.
92.8
92.8
N.A.
100
64.2
0
0
N.A.
N.A.
N.A.
0
71.4
Percent
Protein Identity:
46.8
43.7
N.A.
44
41.4
N.A.
Protein Similarity:
67.6
65.8
N.A.
65.5
59.5
N.A.
P-Site Identity:
40
40
N.A.
40
0
N.A.
P-Site Similarity:
66.6
66.6
N.A.
66.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
44
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
0
0
0
0
0
0
25
7
0
57
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
25
0
0
0
7
0
% I
% Lys:
69
0
0
0
0
0
0
0
69
13
0
0
0
0
0
% K
% Leu:
0
0
0
0
19
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
50
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
44
0
0
0
0
0
0
13
0
0
25
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
38
0
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
44
0
0
25
0
0
0
0
7
13
0
0
% S
% Thr:
0
0
0
19
0
0
0
0
0
13
0
7
0
0
0
% T
% Val:
0
69
0
0
0
69
0
0
0
0
0
32
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% W
% Tyr:
0
0
0
0
0
0
0
69
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% _